MALDI-based imaging mass spectrometry revealed abnormal distribution of phospholipids in colon cancer liver metastasis

We present the results of matrix-assisted laser desorption/ionization (MALDI) imaging and direct molecular identification using tandem mass spectrometry (MS/MS) in colon cancer liver metastasis. Cancer tissue was removed from a Japanese patient and frozen immediately without any fixations. The secti...

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Veröffentlicht in:	Journal of chromatography. B, Analytical technologies in the biomedical and life sciences Analytical technologies in the biomedical and life sciences, 2007-08, Vol.855 (1), p.98-103
Hauptverfasser:	Shimma, Shuichi, Sugiura, Yuki, Hayasaka, Takahiro, Hoshikawa, Yutaka, Noda, Tetsuo, Setou, Mitsutoshi
Format:	Artikel
Sprache:	eng
Schlagworte:	Aging Analysis Analytical, structural and metabolic biochemistry Biological and medical sciences Colon cancer Colonic Neoplasms - pathology Fundamental and applied biological sciences. Psychology General pharmacology Humans Imaging mass spectrometry Liver Neoplasms - metabolism Liver Neoplasms - secondary Medical sciences Molecular imaging Pharmacology. Drug treatments Phospholipids Phospholipids - analysis Phospholipids - chemistry Phospholipids - metabolism Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization - methods Sphingomyelin
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