A flavonoid glycoside isolated from Smilax china L. rhizome in vitro anticancer effects on human cancer cell lines

The anticancer activity of eight crude extracts of Smilax china L. rhizome (SCR) against HeLa cells was assessed by MTT assay and clonogenic assay, the fraction rich in flavonoids had show good activity against HeLa cells. A bioassay-guided separation on this extract lead to the detection of kaempfe...

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Veröffentlicht in:	Journal of ethnopharmacology 2007-08, Vol.113 (1), p.115-124
Hauptverfasser:	Li, Yuan-Li, Gan, Guo-Ping, Zhang, Hui-Zhan, Wu, He-Zhen, Li, Chang-Long, Huang, Yong-Ping, Liu, Yan-Wen, Liu, Jian-Wen
Format:	Artikel
Sprache:	eng
Schlagworte:	antineoplastic agents Antineoplastic Agents, Phytogenic - administration & dosage Antineoplastic Agents, Phytogenic - pharmacology Apoptosis Apoptosis - drug effects bioassays Biological and medical sciences Cell Cycle - drug effects Cell cycle arrest Cell Line, Tumor Cell Proliferation - drug effects chemical constituents of plants cytotoxicity DNA Fragmentation Dose-Response Relationship, Drug Drug Screening Assays, Antitumor Electrophoresis, Agar Gel ethnobotany Flavonoid glycoside Flavonoids - administration & dosage Flavonoids - pharmacology Flow Cytometry G1 Phase - drug effects General pharmacology glucosides Glucosides - administration & dosage Glucosides - pharmacology Glycosides - administration & dosage Glycosides - pharmacology HeLa Cells herbal medicines human cell lines Humans kaempferol Kaempferols - administration & dosage Kaempferols - pharmacology Medical sciences medicinal plants Oriental traditional medicine Pharmacognosy. Homeopathy. Health food Pharmacology. Drug treatments Pinellia plant extracts Plant Extracts - administration & dosage Plant Extracts - pharmacology quantitative analysis rhizomes Smilax Smilax - chemistry Smilax china Smilax china L
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