The shared epitope hypothesis in rheumatoid arthritis: Evaluation of alternative classification criteria in a large UK Caucasian cohort

Objective Many classification systems for the HLA–DRB1 allelic association with rheumatoid arthritis (RA) have been reported, but few have been validated in additional populations. We sought to evaluate 3 different DRB1 allele classification systems in a large cohort of Caucasian RA patients and con...

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Veröffentlicht in:	Arthritis and rheumatism 2008-05, Vol.58 (5), p.1275-1283
Hauptverfasser:	Morgan, Ann W., Haroon‐Rashid, Lubna, Martin, Stephen G., Gooi, Hock‐Chye, Worthington, Jane, Thomson, Wendy, Barrett, Jennifer H., Emery, Paul
Format:	Artikel
Sprache:	eng
Schlagworte:	Arthritis, Rheumatoid - classification Arthritis, Rheumatoid - genetics Biological and medical sciences Diseases of the osteoarticular system Epitopes European Continental Ancestry Group HLA-DR Antigens - genetics HLA-DRB1 Chains Humans Inflammatory joint diseases Medical sciences United Kingdom
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