Altered Interaction Between PSD‐95 and the NMDA Receptor Following Transient Global Ischemia

: The postsynaptic density (PSD) is a cytoskeletal specialization involved in the anchoring of neurotransmitter receptors and in regulating the response of postsynaptic neurons to synaptic stimulation. The postsynaptic protein PSD‐95 binds to NMDA receptor subunits NR2A and NR2B and to signaling mol...

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Veröffentlicht in:	Journal of neurochemistry 2000-01, Vol.74 (1), p.169-178
Hauptverfasser:	Takagi, Norio, Logan, Richard, Teves, Lucy, Wallace, M. Christopher, Gurd, James W.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Biological and medical sciences Dentate Gyrus - metabolism Deoxycholic Acid Detergents Disks Large Homolog 4 Protein GTPase-Activating Proteins - metabolism Hippocampus - metabolism Intracellular Signaling Peptides and Proteins Ischemia Ischemic Attack, Transient - metabolism Kainate receptor Male Medical sciences Membrane Proteins Nerve Tissue Proteins - metabolism Nerve Tissue Proteins - physiology Neurology Neuronal nitric oxide synthase Neuropeptides - chemistry Neuropeptides - metabolism Nitric Oxide Synthase - metabolism Nitric Oxide Synthase Type I NMDA receptor Postsynaptic density Postsynaptic density 95 protein PSD‐95 Rats Rats, Wistar Receptors, Kainic Acid - metabolism Receptors, N-Methyl-D-Aspartate - metabolism Receptors, N-Methyl-D-Aspartate - physiology Solubility Tissue Distribution Vascular diseases and vascular malformations of the nervous system
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