Isolated Atrial Microvascular Dysfunction in Patients With Lone Recurrent Atrial Fibrillation

Isolated Atrial Microvascular Dysfunction in Patients With Lone Recurrent Atrial Fibrillation

Isolated Atrial Microvascular Dysfunction in Patients With Lone Recurrent Atrial Fibrillation Emmanuel I. Skalidis, Michalis I. Hamilos, Ioannis K. Karalis, Gregory Chlouverakis, George E. Kochiadakis, Panos E. Vardas Sixteen patients with lone recurrent atrial fibrillation and 15 control subjects u...

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Veröffentlicht in:Journal of the American College of Cardiology 2008-05, Vol.51 (21), p.2053-2057
Hauptverfasser: Skalidis, Emmanuel I., MD, Hamilos, Michalis I., MD, Karalis, Ioannis K., MD, Chlouverakis, Gregory, PhD, Kochiadakis, George E., MD, Vardas, Panos E., MD, PhD, FESC, FACC
Format: Artikel
Sprache:eng
Schlagworte:
Aged
Atrial Fibrillation - physiopathology
Biological and medical sciences
Blood Flow Velocity
Blood Volume
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Cardiovascular
Cardiovascular disease
Case-Control Studies
Catheters
Confidence intervals
Coronary Circulation - physiology
Coronary vessels
Coronary Vessels - diagnostic imaging
Female
Fourier transforms
Heart
Heart attacks
Heart rate
Humans
Internal Medicine
Ischemia
Male
Medical imaging
Medical sciences
Microcirculation
Middle Aged
Mortality
Pathogenesis
Studies
Ultrasonography, Doppler
Ultrasonography, Interventional
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Zusammenfassung:Isolated Atrial Microvascular Dysfunction in Patients With Lone Recurrent Atrial Fibrillation Emmanuel I. Skalidis, Michalis I. Hamilos, Ioannis K. Karalis, Gregory Chlouverakis, George E. Kochiadakis, Panos E. Vardas Sixteen patients with lone recurrent atrial fibrillation and 15 control subjects underwent coronary flow velocity measurements in the proximal left circumflex coronary artery and left atrial circumflex branch. Coronary flow reserve of the left atrial circumflex branch in patients with lone recurrent atrial fibrillation was significantly lower than in the control subjects, indicating that microvascular dysfunction is a pathophysiologic substrate associated with this arrhythmia.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2008.01.055