A story: unpaired adenosine bases in ribosomal RNAs

In 1985 an analysis of the Escherichia coli 16 S rRNA covariation-based structure model revealed a strong bias for unpaired adenosines. The same analysis revealed that the majority of the G, C, and U bases were paired. These biases are (now) consistent with the high percentage of unpaired adenosine...

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Veröffentlicht in:	Journal of molecular biology 2000-12, Vol.304 (3), p.335-354
Hauptverfasser:	Gutell, R.R, Cannone, J.J, Shang, Z, Du, Y, Serra, M.J
Format:	Artikel
Sprache:	eng
Schlagworte:	adenosine Adenosine - genetics Adenosine - metabolism Bacteria - genetics Base Composition Base Pairing Base Sequence comparative sequence analysis Computational Biology computational biology/bioinformatics Escherichia coli Introns - genetics Molecular Sequence Data RNA structure RNA, Ribosomal - chemistry RNA, Ribosomal - genetics RNA, Ribosomal - metabolism RNA, Ribosomal, 16S - chemistry RNA, Ribosomal, 16S - genetics RNA, Ribosomal, 16S - metabolism RNA, Ribosomal, 23S - chemistry RNA, Ribosomal, 23S - genetics RNA, Ribosomal, 23S - metabolism rRNA 16S rRNA 23S Sequence Alignment Software structure motifs unpaired adenosines
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