Peptide aptamers: powerful new tools for molecular medicine
One of the major goals in molecular medicine is to understand the basis of human diseases at the molecular level and to translate this information into new strategies for diagnosis and therapy. Peptide aptamers represent a novel generation of molecules, which are selected for their intracellular bin...
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| Veröffentlicht in: | Journal of molecular medicine (Berlin, Germany) Germany), 2000-01, Vol.78 (8), p.426-430 |
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| container_end_page | 430 |
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| container_issue | 8 |
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| container_title | Journal of molecular medicine (Berlin, Germany) |
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| creator | HOPPE-SEYLER, Felix BUTZ, Karin |
| description | One of the major goals in molecular medicine is to understand the basis of human diseases at the molecular level and to translate this information into new strategies for diagnosis and therapy. Peptide aptamers represent a novel generation of molecules, which are selected for their intracellular binding to a given target protein. They are useful tools for basic science in blocking the intracellular function of a target protein with high specificity, thereby allowing the study of distinct physiological and pathological processes within living cells. In addition, peptide aptamers provide a basis for the development of novel diagnostic and therapeutic strategies, with implications for a broad variety of different disease entities, including metabolic disorders, infections, and cancer. |
| doi_str_mv | 10.1007/s001090000140 |
| format | Article |
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| subjects | Biological and medical sciences Drug Design Humans Infection - drug therapy Investigative techniques, diagnostic techniques (general aspects) Medical sciences Metabolic Diseases - drug therapy Miscellaneous. Technology Neoplasms - drug therapy Pathology. Cytology. Biochemistry. Spectrometry. Miscellaneous investigative techniques Peptide Library Peptides - chemistry Peptides - pharmacology Peptides - therapeutic use |
| title | Peptide aptamers: powerful new tools for molecular medicine |
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