Acrolein sequestering ability of the endogenous tripeptide glycyl-histidyl-lysine (GHK): characterization of conjugation products by ESI-MSn and theoretical calculations

Acrolein (ACR) is a well-known carbonyl toxin produced by lipid peroxidation of polyunsaturated fatty acids, which is involved in several life-threatening pathologies such as Alzheimer disease, arteriosclerosis, diabetes, and nephropathy. The aim of this work was to study the quenching ability of th...

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Veröffentlicht in:	Journal of pharmaceutical and biomedical analysis 2008-07, Vol.47 (3), p.596-602
Hauptverfasser:	Beretta, Giangiacomo, Arlandini, Emanuele, Artali, Roberto, Anton, Josep M Garcia, Maffei Facino, R
Format:	Artikel
Sprache:	eng
Schlagworte:	Acrolein - chemistry Mathematics Oligopeptides - chemistry Spectrometry, Mass, Electrospray Ionization - methods
Online-Zugang:	Volltext
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