The 2.2 Å resolution structure of the O(H) blood-group-specific lectin I from Ulex europaeus

The tertiary and quaternary structure of the lectin I from Ulex europaeus (UE-I) has been determined to 2.2 Å resolution. UE-I is a dimeric metalloglycoprotein that binds the H-type 2 human blood group determinant [α- l-Fucα(1 → 2)-β- d-Galβ(1 → 4)-β- d-GlcNAcα-]. Nine changes from the published ami...

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Veröffentlicht in:	Journal of molecular biology 2000-12, Vol.304 (3), p.423-433
Hauptverfasser:	Audette, Gerald F, Vandonselaar, Margaret, Delbaere, Louis T.J
Format:	Artikel
Sprache:	eng
Schlagworte:	Binding Sites Calcium - metabolism chemical mapping Crystallography, X-Ray Disulfides - metabolism H-type 2 human blood group determinant Hydrogen Bonding Lectins - chemistry Lectins - metabolism Magnoliopsida - chemistry Manganese - metabolism Methylglycosides - chemistry Methylglycosides - metabolism Models, Molecular Oligosaccharides - chemistry Oligosaccharides - metabolism Plant Lectins Protein Structure, Quaternary Protein Structure, Tertiary protein-carbohydrate interaction Ulex europaeus lectin I Water - chemistry Water - metabolism X-ray crystallography
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