IDMap: facilitating the detection of potential leads with therapeutic targets

Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relati...

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Veröffentlicht in:Bioinformatics 2008-06, Vol.24 (11), p.1413-1415
Hauptverfasser: Ha, Soyang, Seo, Young-Ju, Kwon, Min-Seok, Chang, Byung-Ha, Han, Cheol-Kyu, Yoon, Jeong-Hyeok
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container_end_page 1415
container_issue 11
container_start_page 1413
container_title Bioinformatics
container_volume 24
creator Ha, Soyang
Seo, Young-Ju
Kwon, Min-Seok
Chang, Byung-Ha
Han, Cheol-Kyu
Yoon, Jeong-Hyeok
description Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. Availability: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap Contact: idmap@equispharm.com
doi_str_mv 10.1093/bioinformatics/btn138
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subjects Artificial Intelligence
Biological and medical sciences
Database Management Systems
Databases, Factual
Drug Design
Drug Therapy - methods
Fundamental and applied biological sciences. Psychology
General aspects
Information Storage and Retrieval - methods
Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)
Pharmaceutical Preparations - chemistry
Software
title IDMap: facilitating the detection of potential leads with therapeutic targets
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