IDMap: facilitating the detection of potential leads with therapeutic targets
Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relati...
Gespeichert in:
Veröffentlicht in: | Bioinformatics 2008-06, Vol.24 (11), p.1413-1415 |
---|---|
Hauptverfasser: | , , , , , |
Format: | Artikel |
Sprache: | eng |
Schlagworte: | |
Online-Zugang: | Volltext bestellen |
Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
container_end_page | 1415 |
---|---|
container_issue | 11 |
container_start_page | 1413 |
container_title | Bioinformatics |
container_volume | 24 |
creator | Ha, Soyang Seo, Young-Ju Kwon, Min-Seok Chang, Byung-Ha Han, Cheol-Kyu Yoon, Jeong-Hyeok |
description | Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. Availability: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap Contact: idmap@equispharm.com |
doi_str_mv | 10.1093/bioinformatics/btn138 |
format | Article |
fullrecord | <record><control><sourceid>proquest_TOX</sourceid><recordid>TN_cdi_proquest_miscellaneous_70767822</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><oup_id>10.1093/bioinformatics/btn138</oup_id><sourcerecordid>70767822</sourcerecordid><originalsourceid>FETCH-LOGICAL-c521t-a8db4d1c05ed523e5ad2e90e27d3223b01c0097e4e3791150e81bd4cb25f0693</originalsourceid><addsrcrecordid>eNqNkU9v1DAQxS1ERUvhI4AiJLilHf-LE25oC91KWyGkHhAXy3EmrUs2Tm1HwLfHq6xalUs5jaX5vfc8eoS8oXBCoeGnrfNu7H3YmuRsPG3TSHn9jBxRUUHJQDbP85tXqhQ18EPyMsZbAEmFEC_IIa0FVaJujsjlxdmlmT4WvbFucCmbjddFusGiw4Q2OT8Wvi8mn3BMzgzFgKaLxS-XbnZUMBPOOb9IJlxjiq_IQW-GiK_385hcffl8tVqXm6_nF6tPm9JKRlNp6q4VHbUgsZOMozQdwwaQqY4zxlvIK2gUCuSqoVQC1rTthG2Z7KFq-DH5sNhOwd_NGJPeumhxGMyIfo5agapUnZ2eAllOocAgg-_-AW_9HMZ8g6ZNXVWKU54huUA2-BgD9noKbmvCH01B70rRj0vRSylZ93ZvPrdb7B5U-xYy8H4PmGjN0AczWhfvOQYCQMndL2Hh_Dz9d3a5SFxM-PteZMJPnY9SUq-__9Drs82q-UbXWvK_Kiu6Lg</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>198667313</pqid></control><display><type>article</type><title>IDMap: facilitating the detection of potential leads with therapeutic targets</title><source>Oxford Journals Open Access Collection</source><creator>Ha, Soyang ; Seo, Young-Ju ; Kwon, Min-Seok ; Chang, Byung-Ha ; Han, Cheol-Kyu ; Yoon, Jeong-Hyeok</creator><creatorcontrib>Ha, Soyang ; Seo, Young-Ju ; Kwon, Min-Seok ; Chang, Byung-Ha ; Han, Cheol-Kyu ; Yoon, Jeong-Hyeok</creatorcontrib><description>Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. Availability: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap Contact: idmap@equispharm.com</description><identifier>ISSN: 1367-4803</identifier><identifier>ISSN: 0266-7061</identifier><identifier>EISSN: 1460-2059</identifier><identifier>EISSN: 1367-4811</identifier><identifier>DOI: 10.1093/bioinformatics/btn138</identifier><identifier>PMID: 18417489</identifier><identifier>CODEN: BOINFP</identifier><language>eng</language><publisher>Oxford: Oxford University Press</publisher><subject>Artificial Intelligence ; Biological and medical sciences ; Database Management Systems ; Databases, Factual ; Drug Design ; Drug Therapy - methods ; Fundamental and applied biological sciences. Psychology ; General aspects ; Information Storage and Retrieval - methods ; Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) ; Pharmaceutical Preparations - chemistry ; Software</subject><ispartof>Bioinformatics, 2008-06, Vol.24 (11), p.1413-1415</ispartof><rights>The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org 2008</rights><rights>2008 INIST-CNRS</rights><rights>The Author 2008. Published by Oxford University Press. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c521t-a8db4d1c05ed523e5ad2e90e27d3223b01c0097e4e3791150e81bd4cb25f0693</citedby><cites>FETCH-LOGICAL-c521t-a8db4d1c05ed523e5ad2e90e27d3223b01c0097e4e3791150e81bd4cb25f0693</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,776,780,1598,27901,27902</link.rule.ids><linktorsrc>$$Uhttps://dx.doi.org/10.1093/bioinformatics/btn138$$EView_record_in_Oxford_University_Press$$FView_record_in_$$GOxford_University_Press</linktorsrc><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20400750$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18417489$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Ha, Soyang</creatorcontrib><creatorcontrib>Seo, Young-Ju</creatorcontrib><creatorcontrib>Kwon, Min-Seok</creatorcontrib><creatorcontrib>Chang, Byung-Ha</creatorcontrib><creatorcontrib>Han, Cheol-Kyu</creatorcontrib><creatorcontrib>Yoon, Jeong-Hyeok</creatorcontrib><title>IDMap: facilitating the detection of potential leads with therapeutic targets</title><title>Bioinformatics</title><addtitle>Bioinformatics</addtitle><description>Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. Availability: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap Contact: idmap@equispharm.com</description><subject>Artificial Intelligence</subject><subject>Biological and medical sciences</subject><subject>Database Management Systems</subject><subject>Databases, Factual</subject><subject>Drug Design</subject><subject>Drug Therapy - methods</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>General aspects</subject><subject>Information Storage and Retrieval - methods</subject><subject>Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)</subject><subject>Pharmaceutical Preparations - chemistry</subject><subject>Software</subject><issn>1367-4803</issn><issn>0266-7061</issn><issn>1460-2059</issn><issn>1367-4811</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNqNkU9v1DAQxS1ERUvhI4AiJLilHf-LE25oC91KWyGkHhAXy3EmrUs2Tm1HwLfHq6xalUs5jaX5vfc8eoS8oXBCoeGnrfNu7H3YmuRsPG3TSHn9jBxRUUHJQDbP85tXqhQ18EPyMsZbAEmFEC_IIa0FVaJujsjlxdmlmT4WvbFucCmbjddFusGiw4Q2OT8Wvi8mn3BMzgzFgKaLxS-XbnZUMBPOOb9IJlxjiq_IQW-GiK_385hcffl8tVqXm6_nF6tPm9JKRlNp6q4VHbUgsZOMozQdwwaQqY4zxlvIK2gUCuSqoVQC1rTthG2Z7KFq-DH5sNhOwd_NGJPeumhxGMyIfo5agapUnZ2eAllOocAgg-_-AW_9HMZ8g6ZNXVWKU54huUA2-BgD9noKbmvCH01B70rRj0vRSylZ93ZvPrdb7B5U-xYy8H4PmGjN0AczWhfvOQYCQMndL2Hh_Dz9d3a5SFxM-PteZMJPnY9SUq-__9Drs82q-UbXWvK_Kiu6Lg</recordid><startdate>20080601</startdate><enddate>20080601</enddate><creator>Ha, Soyang</creator><creator>Seo, Young-Ju</creator><creator>Kwon, Min-Seok</creator><creator>Chang, Byung-Ha</creator><creator>Han, Cheol-Kyu</creator><creator>Yoon, Jeong-Hyeok</creator><general>Oxford University Press</general><general>Oxford Publishing Limited (England)</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7QF</scope><scope>7QO</scope><scope>7QQ</scope><scope>7SC</scope><scope>7SE</scope><scope>7SP</scope><scope>7SR</scope><scope>7TA</scope><scope>7TB</scope><scope>7TM</scope><scope>7TO</scope><scope>7U5</scope><scope>8BQ</scope><scope>8FD</scope><scope>F28</scope><scope>FR3</scope><scope>H8D</scope><scope>H8G</scope><scope>H94</scope><scope>JG9</scope><scope>JQ2</scope><scope>K9.</scope><scope>KR7</scope><scope>L7M</scope><scope>L~C</scope><scope>L~D</scope><scope>P64</scope><scope>7X8</scope></search><sort><creationdate>20080601</creationdate><title>IDMap: facilitating the detection of potential leads with therapeutic targets</title><author>Ha, Soyang ; Seo, Young-Ju ; Kwon, Min-Seok ; Chang, Byung-Ha ; Han, Cheol-Kyu ; Yoon, Jeong-Hyeok</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c521t-a8db4d1c05ed523e5ad2e90e27d3223b01c0097e4e3791150e81bd4cb25f0693</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Artificial Intelligence</topic><topic>Biological and medical sciences</topic><topic>Database Management Systems</topic><topic>Databases, Factual</topic><topic>Drug Design</topic><topic>Drug Therapy - methods</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>General aspects</topic><topic>Information Storage and Retrieval - methods</topic><topic>Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects)</topic><topic>Pharmaceutical Preparations - chemistry</topic><topic>Software</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Ha, Soyang</creatorcontrib><creatorcontrib>Seo, Young-Ju</creatorcontrib><creatorcontrib>Kwon, Min-Seok</creatorcontrib><creatorcontrib>Chang, Byung-Ha</creatorcontrib><creatorcontrib>Han, Cheol-Kyu</creatorcontrib><creatorcontrib>Yoon, Jeong-Hyeok</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Aluminium Industry Abstracts</collection><collection>Biotechnology Research Abstracts</collection><collection>Ceramic Abstracts</collection><collection>Computer and Information Systems Abstracts</collection><collection>Corrosion Abstracts</collection><collection>Electronics & Communications Abstracts</collection><collection>Engineered Materials Abstracts</collection><collection>Materials Business File</collection><collection>Mechanical & Transportation Engineering Abstracts</collection><collection>Nucleic Acids Abstracts</collection><collection>Oncogenes and Growth Factors Abstracts</collection><collection>Solid State and Superconductivity Abstracts</collection><collection>METADEX</collection><collection>Technology Research Database</collection><collection>ANTE: Abstracts in New Technology & Engineering</collection><collection>Engineering Research Database</collection><collection>Aerospace Database</collection><collection>Copper Technical Reference Library</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>Materials Research Database</collection><collection>ProQuest Computer Science Collection</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Civil Engineering Abstracts</collection><collection>Advanced Technologies Database with Aerospace</collection><collection>Computer and Information Systems Abstracts Academic</collection><collection>Computer and Information Systems Abstracts Professional</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>MEDLINE - Academic</collection><jtitle>Bioinformatics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>Ha, Soyang</au><au>Seo, Young-Ju</au><au>Kwon, Min-Seok</au><au>Chang, Byung-Ha</au><au>Han, Cheol-Kyu</au><au>Yoon, Jeong-Hyeok</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>IDMap: facilitating the detection of potential leads with therapeutic targets</atitle><jtitle>Bioinformatics</jtitle><addtitle>Bioinformatics</addtitle><date>2008-06-01</date><risdate>2008</risdate><volume>24</volume><issue>11</issue><spage>1413</spage><epage>1415</epage><pages>1413-1415</pages><issn>1367-4803</issn><issn>0266-7061</issn><eissn>1460-2059</eissn><eissn>1367-4811</eissn><coden>BOINFP</coden><abstract>Pharmaceutical industry has been striving to reduce the costs of drug development and increase productivity. Among the many different attempts, drug repositioning (retargeting existing drugs) comes into the spotlight because of its financial efficiency. We introduce IDMap which predicts novel relationships between targets and chemicals and thus is capable of repositioning the marketed drugs by using text mining and chemical structure information. Also capable of mapping commercial chemicals to possible drug targets and vice versa, IDMap creates convenient environments for identifying the potential lead and its targets, especially in the field of drug repositioning. Availability: IDMap executable and its user manual including color images are freely available to non-commercial users at http://www.equispharm.com/idmap Contact: idmap@equispharm.com</abstract><cop>Oxford</cop><pub>Oxford University Press</pub><pmid>18417489</pmid><doi>10.1093/bioinformatics/btn138</doi><tpages>3</tpages><oa>free_for_read</oa></addata></record> |
fulltext | fulltext_linktorsrc |
identifier | ISSN: 1367-4803 |
ispartof | Bioinformatics, 2008-06, Vol.24 (11), p.1413-1415 |
issn | 1367-4803 0266-7061 1460-2059 1367-4811 |
language | eng |
recordid | cdi_proquest_miscellaneous_70767822 |
source | Oxford Journals Open Access Collection |
subjects | Artificial Intelligence Biological and medical sciences Database Management Systems Databases, Factual Drug Design Drug Therapy - methods Fundamental and applied biological sciences. Psychology General aspects Information Storage and Retrieval - methods Mathematics in biology. Statistical analysis. Models. Metrology. Data processing in biology (general aspects) Pharmaceutical Preparations - chemistry Software |
title | IDMap: facilitating the detection of potential leads with therapeutic targets |
url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-15T23%3A26%3A48IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_TOX&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=IDMap:%20facilitating%20the%20detection%20of%20potential%20leads%20with%20therapeutic%20targets&rft.jtitle=Bioinformatics&rft.au=Ha,%20Soyang&rft.date=2008-06-01&rft.volume=24&rft.issue=11&rft.spage=1413&rft.epage=1415&rft.pages=1413-1415&rft.issn=1367-4803&rft.eissn=1460-2059&rft.coden=BOINFP&rft_id=info:doi/10.1093/bioinformatics/btn138&rft_dat=%3Cproquest_TOX%3E70767822%3C/proquest_TOX%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=198667313&rft_id=info:pmid/18417489&rft_oup_id=10.1093/bioinformatics/btn138&rfr_iscdi=true |