Hydrogen sulfide regulates lung tissue-oxidized glutathione and total antioxidant capacity in hypoxic pulmonary hypertensive rats

Aim： To investigate the modulatory effect of sudium hydrosulfide on lung tissueoxidized glutathione and total antioxidant capacity in the development of hypoxic pulmonary hypertension （HPH）. Methods： After 21 d of hypoxia, the mean pulmonary artery pressure was measured by cardiac catheterization. T...

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Veröffentlicht in:	Acta pharmacologica Sinica 2008-06, Vol.29 (6), p.670-676
Hauptverfasser:	Wei, Hong-ling, Zhang, Chun-yu, Jin, Hong-fang, Tang, Chao-shu, Du, Jun-bao
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antioxidants - metabolism Biomedical and Life Sciences Biomedicine Glutathione - metabolism Hemodynamics - drug effects Hydrogen Sulfide - blood Hydrogen Sulfide - pharmacology Hypertension, Pulmonary - metabolism Hypertension, Pulmonary - physiopathology Immunology Internal Medicine Lung - drug effects Lung - enzymology Lung - metabolism Male Medical Microbiology original-article Oxidation-Reduction Oxidative Stress - drug effects Pharmacology/Toxicology Rats Rats, Wistar RNA, Messenger - biosynthesis RNA, Messenger - genetics Superoxide Dismutase - biosynthesis Superoxide Dismutase - genetics Vaccine 氧化应力硫化氢缺氧症肺部高血压超氧化物歧化酶
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