The role of elastoviscosity in the efficacy of viscosupplementation for osteoarthritis of the knee: A comparison of Hylan G-F 20 and a lower-molecular-weight hyaluronan

The objective of this 12-week, doublemasked, randomized, multicenter study was to compare the elastoviscous properties of a high-molecular-weight viscosupplement, hylan G-F 20 (polymer concentration, 0.8%), with those of a lower-molecularweight hyaluronan (LMW HA) product (polymer concentration, 1%)...

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Veröffentlicht in:	Clinical therapeutics 1999-09, Vol.21 (9), p.1549-1562
Hauptverfasser:	Wobig, Manfred, Bach, Gerhard, Beks, Pieter, Dickhut, Adalbert, Runzheimer, Joost, Schwieger, Gottfried, Vetter, Georg, Balazs, Endre
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult Aged Biological and medical sciences Bones, joints and connective tissue. Antiinflammatory agents Cellulose - therapeutic use Double-Blind Method Drug Combinations Elasticity elastoviscosity Female Hexamethonium Compounds - therapeutic use Humans hyaluronan Hyaluronic Acid - administration & dosage Hyaluronic Acid - analogs & derivatives Hyaluronic Acid - therapeutic use hylan Injections, Intra-Articular Joint Diseases - therapy knee Knee Joint Male Medical sciences Middle Aged Molecular Weight osteoarthritis Osteoarthritis - therapy Pain Measurement Pharmacology. Drug treatments Polymers - chemistry Tantalum - therapeutic use Thrombin - therapeutic use Time Factors Treatment Outcome Viscosity viscosupplementation
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