Capillary electrophoresis-electrospray-mass spectrometry in peptide analysis and peptidomics
In the present work, an exhaustive review of the main developments and applications of CE-MS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different mu...
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| Veröffentlicht in: | Electrophoresis 2008-05, Vol.29 (10), p.2148-2160 |
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| container_title | Electrophoresis |
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| creator | Herrero, Miguel Ibañez, Elena Cifuentes, Alejandro |
| description | In the present work, an exhaustive review of the main developments and applications of CE-MS for peptide analysis is given. This review includes the use of different CE separation modes, MS analyzers, capillary coatings, preconcentration techniques, on-chip applications as well as other different multidimensional strategies for peptide analysis. Key applications are critically discussed and relevant works published from January 2000 to May 2007 are summarized including information concerning the type of sample, CE-MS parameters as well as some figures of merit of the different CE-MS procedures developed for peptide analysis and peptidomics. |
| doi_str_mv | 10.1002/elps.200700404 |
| format | Article |
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| ispartof | Electrophoresis, 2008-05, Vol.29 (10), p.2148-2160 |
| issn | 0173-0835 1522-2683 |
| language | eng |
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| source | MEDLINE; Wiley Online Library All Journals |
| subjects | Animals Capillary electrophoresis-mass spectrometry Electrophoresis, Capillary - instrumentation Electrophoresis, Capillary - methods Electrophoresis, Microchip - instrumentation Electrophoresis, Microchip - methods Equipment Design Humans Peptides Peptides - analysis Protein Array Analysis - instrumentation Protein Array Analysis - methods Proteomics Proteomics - methods Silicon Dioxide Spectrometry, Mass, Electrospray Ionization - instrumentation Spectrometry, Mass, Electrospray Ionization - methods |
| title | Capillary electrophoresis-electrospray-mass spectrometry in peptide analysis and peptidomics |
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