CD248/Endosialin is dynamically expressed on a subset of stromal cells during lymphoid tissue development, splenic remodeling and repair

Studies of stromal cell populations in lymphoid tissue (LT) have been hampered by a lack of selective markers. Here, we show that CD248 (Endosialin/TEM1) is a stromal marker that is differentially expressed on fibroblasts and pericytes in the thymus, lymph node and spleen. Expression is high during...

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Veröffentlicht in:	FEBS letters 2007-07, Vol.581 (18), p.3550-3556
Hauptverfasser:	Lax, Siân, Hou, Tie Zheng, Jenkinson, Eric, Salmon, Mike, MacFadyen, John R., Isacke, Clare M., Anderson, Graham, Cunningham, Adam F., Buckley, Christopher D.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antigens, CD - metabolism B-Lymphocytes - metabolism Biomarkers CD248 Cell Count Gene Expression Regulation, Developmental lymphoid tissue Lymphoid Tissue - embryology Lymphoid Tissue - metabolism Mice Mice, Inbred C57BL Neoplasm Proteins - metabolism Platelet Endothelial Cell Adhesion Molecule-1 - metabolism Salmonella Salmonella Infections - metabolism Salmonella Infections - pathology Salmonidae Spleen - embryology Spleen - metabolism Stromal cells Stromal Cells - metabolism Time Factors Tissue repair
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