Partial Thrombosis of the False Lumen in Patients with Acute Type B Aortic Dissection
A cohort of 201 patients with type B acute aortic dissection was classified according to whether the false lumen of the aorta was patent, partially thrombosed, or completely thrombosed. Patients with partial thrombosis had a significantly higher mortality rate at 3 years. In patients with type B acu...
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| Veröffentlicht in: | The New England journal of medicine 2007-07, Vol.357 (4), p.349-359 |
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| creator | Tsai, Thomas T Evangelista, Arturo Nienaber, Christoph A Myrmel, Truls Meinhardt, Gabriel Cooper, Jeanna V Smith, Dean E Suzuki, Toru Fattori, Rossella Llovet, Alfredo Froehlich, James Hutchison, Stuart Distante, Alessandro Sundt, Thoralf Beckman, Joshua Januzzi, James L Isselbacher, Eric M Eagle, Kim A |
| description | A cohort of 201 patients with type B acute aortic dissection was classified according to whether the false lumen of the aorta was patent, partially thrombosed, or completely thrombosed. Patients with partial thrombosis had a significantly higher mortality rate at 3 years.
In patients with type B acute aortic dissection, those with partial thrombosis had a significantly higher mortality rate at 3 years.
Acute aortic dissection is a dangerous condition with high in-hospital and follow-up mortality rates. Dissections confined to the descending aorta (type B) have better in-hospital survival than those involving the ascending aorta (type A). Up to 89% of patients with uncomplicated type B dissections survive to hospital discharge after receiving effective antihypertensive therapy.
1
However, despite a low in-hospital mortality, the short- and long-term prognosis of patients with type B acute aortic dissection after discharge from the hospital is heterogeneous, with reported survival rates ranging from 56 to 92% at 1 year and from 48 to 82% at 5 years.
2
– . . . |
| doi_str_mv | 10.1056/NEJMoa063232 |
| format | Article |
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In patients with type B acute aortic dissection, those with partial thrombosis had a significantly higher mortality rate at 3 years.
Acute aortic dissection is a dangerous condition with high in-hospital and follow-up mortality rates. Dissections confined to the descending aorta (type B) have better in-hospital survival than those involving the ascending aorta (type A). Up to 89% of patients with uncomplicated type B dissections survive to hospital discharge after receiving effective antihypertensive therapy.
1
However, despite a low in-hospital mortality, the short- and long-term prognosis of patients with type B acute aortic dissection after discharge from the hospital is heterogeneous, with reported survival rates ranging from 56 to 92% at 1 year and from 48 to 82% at 5 years.
2
– . . .</description><identifier>ISSN: 0028-4793</identifier><identifier>EISSN: 1533-4406</identifier><identifier>DOI: 10.1056/NEJMoa063232</identifier><identifier>PMID: 17652650</identifier><identifier>CODEN: NEJMAG</identifier><language>eng</language><publisher>Boston, MA: Massachusetts Medical Society</publisher><subject>Acute Disease ; Age Factors ; Aged ; Aneurysm, Dissecting - complications ; Aneurysm, Dissecting - mortality ; Aortic Aneurysm - complications ; Aortic Aneurysm - mortality ; Biological and medical sciences ; Blood and lymphatic vessels ; Blood clots ; Cardiology. Vascular system ; Cardiovascular disease ; Coronary vessels ; Discharge ; Diseases of the aorta ; Female ; Follow-Up Studies ; General aspects ; Humans ; Incidence ; Kaplan-Meier Estimate ; Male ; Medical prognosis ; Medical sciences ; Middle Aged ; Mortality ; Prognosis ; Registries ; Risk ; Thrombosis - diagnosis ; Thrombosis - epidemiology ; Thrombosis - etiology ; Vascular Patency</subject><ispartof>The New England journal of medicine, 2007-07, Vol.357 (4), p.349-359</ispartof><rights>Copyright © 2007 Massachusetts Medical Society. All rights reserved.</rights><rights>2007 INIST-CNRS</rights><rights>Copyright 2007 Massachusetts Medical Society.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c543t-4e3540637b018d081ab319e74498c58ca6bc0d32e884d76a518021784d6b31ae3</citedby><cites>FETCH-LOGICAL-c543t-4e3540637b018d081ab319e74498c58ca6bc0d32e884d76a518021784d6b31ae3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.nejm.org/doi/pdf/10.1056/NEJMoa063232$$EPDF$$P50$$Gmms$$H</linktopdf><linktohtml>$$Uhttps://www.proquest.com/docview/223930728?pq-origsite=primo$$EHTML$$P50$$Gproquest$$H</linktohtml><link.rule.ids>315,782,786,2763,2764,26112,27933,27934,52391,54073,64394,64396,64398,72478</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18943258$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17652650$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Tsai, Thomas T</creatorcontrib><creatorcontrib>Evangelista, Arturo</creatorcontrib><creatorcontrib>Nienaber, Christoph A</creatorcontrib><creatorcontrib>Myrmel, Truls</creatorcontrib><creatorcontrib>Meinhardt, Gabriel</creatorcontrib><creatorcontrib>Cooper, Jeanna V</creatorcontrib><creatorcontrib>Smith, Dean E</creatorcontrib><creatorcontrib>Suzuki, Toru</creatorcontrib><creatorcontrib>Fattori, Rossella</creatorcontrib><creatorcontrib>Llovet, Alfredo</creatorcontrib><creatorcontrib>Froehlich, James</creatorcontrib><creatorcontrib>Hutchison, Stuart</creatorcontrib><creatorcontrib>Distante, Alessandro</creatorcontrib><creatorcontrib>Sundt, Thoralf</creatorcontrib><creatorcontrib>Beckman, Joshua</creatorcontrib><creatorcontrib>Januzzi, James L</creatorcontrib><creatorcontrib>Isselbacher, Eric M</creatorcontrib><creatorcontrib>Eagle, Kim A</creatorcontrib><creatorcontrib>International Registry of Acute Aortic Dissection</creatorcontrib><title>Partial Thrombosis of the False Lumen in Patients with Acute Type B Aortic Dissection</title><title>The New England journal of medicine</title><addtitle>N Engl J Med</addtitle><description>A cohort of 201 patients with type B acute aortic dissection was classified according to whether the false lumen of the aorta was patent, partially thrombosed, or completely thrombosed. Patients with partial thrombosis had a significantly higher mortality rate at 3 years.
In patients with type B acute aortic dissection, those with partial thrombosis had a significantly higher mortality rate at 3 years.
Acute aortic dissection is a dangerous condition with high in-hospital and follow-up mortality rates. Dissections confined to the descending aorta (type B) have better in-hospital survival than those involving the ascending aorta (type A). Up to 89% of patients with uncomplicated type B dissections survive to hospital discharge after receiving effective antihypertensive therapy.
1
However, despite a low in-hospital mortality, the short- and long-term prognosis of patients with type B acute aortic dissection after discharge from the hospital is heterogeneous, with reported survival rates ranging from 56 to 92% at 1 year and from 48 to 82% at 5 years.
2
– . . .</description><subject>Acute Disease</subject><subject>Age Factors</subject><subject>Aged</subject><subject>Aneurysm, Dissecting - complications</subject><subject>Aneurysm, Dissecting - mortality</subject><subject>Aortic Aneurysm - complications</subject><subject>Aortic Aneurysm - mortality</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Blood clots</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular disease</subject><subject>Coronary vessels</subject><subject>Discharge</subject><subject>Diseases of the aorta</subject><subject>Female</subject><subject>Follow-Up Studies</subject><subject>General aspects</subject><subject>Humans</subject><subject>Incidence</subject><subject>Kaplan-Meier Estimate</subject><subject>Male</subject><subject>Medical prognosis</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Mortality</subject><subject>Prognosis</subject><subject>Registries</subject><subject>Risk</subject><subject>Thrombosis - diagnosis</subject><subject>Thrombosis - epidemiology</subject><subject>Thrombosis - etiology</subject><subject>Vascular Patency</subject><issn>0028-4793</issn><issn>1533-4406</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNpt0EtrGzEUBWARGmIn6a7rIkrbVabRc6RZuo7zKE6ahb0eNPI1lpkZOZKGkn8fGRtSSrURgk_nXg5Cnyj5QYksr59mvx69ISVnnJ2gMZWcF0KQ8gMaE8J0IVTFR-g8xi3Jh4rqDI2oKiUrJRmj5bMJyZkWLzbBd42PLmK_xmkD-Na0EfB86KDHrsfPJjnoU8R_XNrgiR0S4MXrDvBPPPE5w-IbFyPY5Hx_iU7X-98fj_cFWt7OFtP7Yv777mE6mRdWCp4KAVzmTblqCNUroqlpOK1ACVFpK7U1ZWPJijPQWqxUaSTVhFGVH2WGBvgF-n7I3QX_MkBMdeeihbY1Pfgh1ooomTtiGX75B279EPq8W80YrzhRTGd0dUA2-BgDrOtdcJ0JrzUl9b7r-u-uM_98zByaDlbv-FhuBt-OwERr2nUwvXXx3elKcCb3c78eXNfFuodt9_95b6-vjxo</recordid><startdate>20070726</startdate><enddate>20070726</enddate><creator>Tsai, Thomas T</creator><creator>Evangelista, Arturo</creator><creator>Nienaber, Christoph A</creator><creator>Myrmel, Truls</creator><creator>Meinhardt, Gabriel</creator><creator>Cooper, Jeanna V</creator><creator>Smith, Dean E</creator><creator>Suzuki, Toru</creator><creator>Fattori, Rossella</creator><creator>Llovet, Alfredo</creator><creator>Froehlich, James</creator><creator>Hutchison, Stuart</creator><creator>Distante, Alessandro</creator><creator>Sundt, Thoralf</creator><creator>Beckman, Joshua</creator><creator>Januzzi, James L</creator><creator>Isselbacher, Eric M</creator><creator>Eagle, Kim A</creator><general>Massachusetts Medical Society</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>0TZ</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8AO</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>AN0</scope><scope>AZQEC</scope><scope>BBNVY</scope><scope>BEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K0Y</scope><scope>LK8</scope><scope>M0R</scope><scope>M0T</scope><scope>M1P</scope><scope>M2M</scope><scope>M2O</scope><scope>M2P</scope><scope>M7P</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>PSYQQ</scope><scope>Q9U</scope><scope>7X8</scope></search><sort><creationdate>20070726</creationdate><title>Partial Thrombosis of the False Lumen in Patients with Acute Type B Aortic Dissection</title><author>Tsai, Thomas T ; Evangelista, Arturo ; Nienaber, Christoph A ; Myrmel, Truls ; Meinhardt, Gabriel ; Cooper, Jeanna V ; Smith, Dean E ; Suzuki, Toru ; Fattori, Rossella ; Llovet, Alfredo ; Froehlich, James ; Hutchison, Stuart ; Distante, Alessandro ; Sundt, Thoralf ; Beckman, Joshua ; Januzzi, James L ; Isselbacher, Eric M ; Eagle, Kim A</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c543t-4e3540637b018d081ab319e74498c58ca6bc0d32e884d76a518021784d6b31ae3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Acute Disease</topic><topic>Age Factors</topic><topic>Aged</topic><topic>Aneurysm, Dissecting - complications</topic><topic>Aneurysm, Dissecting - mortality</topic><topic>Aortic Aneurysm - complications</topic><topic>Aortic Aneurysm - mortality</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Blood clots</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular disease</topic><topic>Coronary vessels</topic><topic>Discharge</topic><topic>Diseases of the aorta</topic><topic>Female</topic><topic>Follow-Up Studies</topic><topic>General aspects</topic><topic>Humans</topic><topic>Incidence</topic><topic>Kaplan-Meier Estimate</topic><topic>Male</topic><topic>Medical prognosis</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Mortality</topic><topic>Prognosis</topic><topic>Registries</topic><topic>Risk</topic><topic>Thrombosis - diagnosis</topic><topic>Thrombosis - epidemiology</topic><topic>Thrombosis - etiology</topic><topic>Vascular Patency</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Tsai, Thomas T</creatorcontrib><creatorcontrib>Evangelista, Arturo</creatorcontrib><creatorcontrib>Nienaber, Christoph A</creatorcontrib><creatorcontrib>Myrmel, Truls</creatorcontrib><creatorcontrib>Meinhardt, Gabriel</creatorcontrib><creatorcontrib>Cooper, Jeanna V</creatorcontrib><creatorcontrib>Smith, Dean E</creatorcontrib><creatorcontrib>Suzuki, Toru</creatorcontrib><creatorcontrib>Fattori, Rossella</creatorcontrib><creatorcontrib>Llovet, Alfredo</creatorcontrib><creatorcontrib>Froehlich, James</creatorcontrib><creatorcontrib>Hutchison, Stuart</creatorcontrib><creatorcontrib>Distante, Alessandro</creatorcontrib><creatorcontrib>Sundt, Thoralf</creatorcontrib><creatorcontrib>Beckman, Joshua</creatorcontrib><creatorcontrib>Januzzi, James L</creatorcontrib><creatorcontrib>Isselbacher, Eric M</creatorcontrib><creatorcontrib>Eagle, Kim A</creatorcontrib><creatorcontrib>International Registry of Acute Aortic Dissection</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>Pharma and Biotech Premium PRO</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>ProQuest Pharma Collection</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>British Nursing Database</collection><collection>ProQuest Central Essentials</collection><collection>Biological Science Collection</collection><collection>eLibrary</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>New England Journal of Medicine</collection><collection>ProQuest Biological Science Collection</collection><collection>Consumer Health Database</collection><collection>Healthcare Administration Database</collection><collection>Medical Database</collection><collection>Psychology Database</collection><collection>Research Library</collection><collection>Science Database</collection><collection>Biological Science Database</collection><collection>Research Library (Corporate)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest One Psychology</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><jtitle>The New England journal of medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Tsai, Thomas T</au><au>Evangelista, Arturo</au><au>Nienaber, Christoph A</au><au>Myrmel, Truls</au><au>Meinhardt, Gabriel</au><au>Cooper, Jeanna V</au><au>Smith, Dean E</au><au>Suzuki, Toru</au><au>Fattori, Rossella</au><au>Llovet, Alfredo</au><au>Froehlich, James</au><au>Hutchison, Stuart</au><au>Distante, Alessandro</au><au>Sundt, Thoralf</au><au>Beckman, Joshua</au><au>Januzzi, James L</au><au>Isselbacher, Eric M</au><au>Eagle, Kim A</au><aucorp>International Registry of Acute Aortic Dissection</aucorp><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Partial Thrombosis of the False Lumen in Patients with Acute Type B Aortic Dissection</atitle><jtitle>The New England journal of medicine</jtitle><addtitle>N Engl J Med</addtitle><date>2007-07-26</date><risdate>2007</risdate><volume>357</volume><issue>4</issue><spage>349</spage><epage>359</epage><pages>349-359</pages><issn>0028-4793</issn><eissn>1533-4406</eissn><coden>NEJMAG</coden><abstract>A cohort of 201 patients with type B acute aortic dissection was classified according to whether the false lumen of the aorta was patent, partially thrombosed, or completely thrombosed. Patients with partial thrombosis had a significantly higher mortality rate at 3 years.
In patients with type B acute aortic dissection, those with partial thrombosis had a significantly higher mortality rate at 3 years.
Acute aortic dissection is a dangerous condition with high in-hospital and follow-up mortality rates. Dissections confined to the descending aorta (type B) have better in-hospital survival than those involving the ascending aorta (type A). Up to 89% of patients with uncomplicated type B dissections survive to hospital discharge after receiving effective antihypertensive therapy.
1
However, despite a low in-hospital mortality, the short- and long-term prognosis of patients with type B acute aortic dissection after discharge from the hospital is heterogeneous, with reported survival rates ranging from 56 to 92% at 1 year and from 48 to 82% at 5 years.
2
– . . .</abstract><cop>Boston, MA</cop><pub>Massachusetts Medical Society</pub><pmid>17652650</pmid><doi>10.1056/NEJMoa063232</doi><tpages>11</tpages><oa>free_for_read</oa></addata></record> |
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| subjects | Acute Disease Age Factors Aged Aneurysm, Dissecting - complications Aneurysm, Dissecting - mortality Aortic Aneurysm - complications Aortic Aneurysm - mortality Biological and medical sciences Blood and lymphatic vessels Blood clots Cardiology. Vascular system Cardiovascular disease Coronary vessels Discharge Diseases of the aorta Female Follow-Up Studies General aspects Humans Incidence Kaplan-Meier Estimate Male Medical prognosis Medical sciences Middle Aged Mortality Prognosis Registries Risk Thrombosis - diagnosis Thrombosis - epidemiology Thrombosis - etiology Vascular Patency |
| title | Partial Thrombosis of the False Lumen in Patients with Acute Type B Aortic Dissection |
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