Monokine induced by interferon gamma and IFN-γ response to a fusion protein of Mycobacterium tuberculosis ESAT-6 and CFP-10 in Brazilian tuberculosis patients

IFN-γ responses to Mycobacterium tuberculosis antigens ESAT-6 and CFP-10 have been proposed as specific markers of M. tuberculosis infection. Monokine induced by gamma interferon (MIG/CXCL9) has been shown to be expressed by IFN-γ stimulated mononuclear cells and to attract activated T-cells through...

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Veröffentlicht in:	Microbes and infection 2006, Vol.8 (1), p.45-51
Hauptverfasser:	Abramo, Clarice, Meijgaarden, Krista E., Garcia, Daniely, Franken, Kees L.M.C., Klein, Michèl R., Kolk, Arend J., Oliveira, Sérgio C., Ottenhoff, Tom H.M., Teixeira, Henrique C.
Format:	Artikel
Sprache:	eng
Schlagworte:	Ag85B Antigens, Bacterial - pharmacology Brazil Chemokine CXCL9 Chemokines, CXC - metabolism ESAT-6/CFP-10 Humans IFN-γ Intercellular Signaling Peptides and Proteins - metabolism Interferon-gamma - metabolism Leukocytes, Mononuclear - drug effects Leukocytes, Mononuclear - metabolism MIG (CXCL9) Mycobacterium tuberculosis Mycobacterium tuberculosis - metabolism PPD Recombinant Fusion Proteins - pharmacology Tuberculin - pharmacology Tuberculosis Tuberculosis - metabolism
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