Functional analysis of myelodysplastic syndromes-derived mesenchymal stem cells

Abstract Two different reports, including one from our own group, have recently demonstrated the presence of severe chromosomal abnormalities in mesenchymal stem cells (MSC) from patients with myelodysplastic syndromes (MDS). In the present study, we have assessed whether such cytogenetic abnormalit...

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Veröffentlicht in:	Leukemia research 2008-09, Vol.32 (9), p.1407-1416
Hauptverfasser:	Flores-Figueroa, Eugenia, Montesinos, Juan José, Flores-Guzmán, Patricia, Gutiérrez-Espíndola, Guillermo, Arana-Trejo, Rosa María, Castillo-Medina, Sebastián, Pérez-Cabrera, Adrián, Hernández-Estévez, Erika, Arriaga, Lourdes, Mayani, Hector
Format:	Artikel
Sprache:	eng
Schlagworte:	Adipocytes - cytology Adipocytes - metabolism Adolescent Adult Cell Adhesion Molecules - metabolism Cell Differentiation Cells, Cultured Chondrocytes - cytology Chondrocytes - metabolism Coculture Techniques Colony-Forming Units Assay Cytogenetic Analysis Extracellular Matrix Proteins - metabolism Fetal Blood - cytology Fetal Blood - metabolism Hematology, Oncology and Palliative Medicine Humans Interleukin-1beta - metabolism Mesenchymal stem cells Mesenchymal Stromal Cells - metabolism Microenvironment Middle Aged Myelodysplasia Myelodysplastic Syndromes - metabolism Myelodysplastic Syndromes - pathology Niche Osteoblasts - cytology Osteoblasts - metabolism Stroma TNFα Tumor Necrosis Factor-alpha - metabolism
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