Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine
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| Veröffentlicht in: | Antimicrobial Agents and Chemotherapy 2007-08, Vol.51 (8), p.2701-2708 |
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| creator | NAKATA, Hirotomo AMANO, Masayuki CHENG, Yung-Chi MITSUYA, Hiroaki KOH, Yasuhiro KODAMA, Eiichi GUANGWEI YANG BAILEY, Christopher M KOHGO, Satoru HAYAKAWA, Hiroyuki MATSUOKA, Masao ANDERSON, Karen S |
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| doi_str_mv | 10.1128/aac.00277-07 |
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</description><identifier>ISSN: 0066-4804</identifier><identifier>EISSN: 1098-6596</identifier><identifier>DOI: 10.1128/aac.00277-07</identifier><identifier>PMID: 17548498</identifier><identifier>CODEN: AACHAX</identifier><language>eng</language><publisher>Washington, DC: American Society for Microbiology</publisher><subject>Anti-HIV Agents ; Anti-HIV Agents - chemistry ; Anti-HIV Agents - metabolism ; Anti-HIV Agents - pharmacology ; Antibiotics. Antiinfectious agents. Antiparasitic agents ; Antiviral Agents ; Biological and medical sciences ; CD4-Positive T-Lymphocytes ; Cells, Cultured ; Culture Media ; Deoxyadenosines ; Deoxyadenosines - chemistry ; Deoxyadenosines - metabolism ; Deoxyadenosines - pharmacology ; DNA-Directed DNA Polymerase ; DNA-Directed DNA Polymerase - drug effects ; HIV-1 ; HIV-1 - drug effects ; Human immunodeficiency virus 1 ; Human viral diseases ; Humans ; Immunodeficiencies ; Immunodeficiencies. Immunoglobulinopathies ; Immunopathology ; Infectious diseases ; Medical sciences ; Microbial Sensitivity Tests ; Pharmacology. Drug treatments ; Reverse Transcriptase Inhibitors ; Reverse Transcriptase Inhibitors - chemistry ; Reverse Transcriptase Inhibitors - metabolism ; Reverse Transcriptase Inhibitors - pharmacology ; Tritium - metabolism ; Viral diseases ; Viral diseases of the lymphoid tissue and the blood. Aids ; Zidovudine - metabolism ; Zidovudine - pharmacology</subject><ispartof>Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.2701-2708</ispartof><rights>2007 INIST-CNRS</rights><rights>Copyright © 2007 American Society for Microbiology</rights><rights>Copyright © 2007, American Society for Microbiology 2007</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-a569t-ce5bde3f6d0a19ebc03b2faf22ae5e9860d306be89c27088f1f2c71aef901ba3</citedby><cites>FETCH-LOGICAL-a569t-ce5bde3f6d0a19ebc03b2faf22ae5e9860d306be89c27088f1f2c71aef901ba3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1932487/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC1932487/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,724,777,781,882,27905,27906,53772,53774</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=18962990$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17548498$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>NAKATA, Hirotomo</creatorcontrib><creatorcontrib>AMANO, Masayuki</creatorcontrib><creatorcontrib>CHENG, Yung-Chi</creatorcontrib><creatorcontrib>MITSUYA, Hiroaki</creatorcontrib><creatorcontrib>KOH, Yasuhiro</creatorcontrib><creatorcontrib>KODAMA, Eiichi</creatorcontrib><creatorcontrib>GUANGWEI YANG</creatorcontrib><creatorcontrib>BAILEY, Christopher M</creatorcontrib><creatorcontrib>KOHGO, Satoru</creatorcontrib><creatorcontrib>HAYAKAWA, Hiroyuki</creatorcontrib><creatorcontrib>MATSUOKA, Masao</creatorcontrib><creatorcontrib>ANDERSON, Karen S</creatorcontrib><title>Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine</title><title>Antimicrobial Agents and Chemotherapy</title><addtitle>AAC</addtitle><addtitle>Antimicrob Agents Chemother</addtitle><description>Classifications
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</description><subject>Anti-HIV Agents</subject><subject>Anti-HIV Agents - chemistry</subject><subject>Anti-HIV Agents - metabolism</subject><subject>Anti-HIV Agents - pharmacology</subject><subject>Antibiotics. Antiinfectious agents. Antiparasitic agents</subject><subject>Antiviral Agents</subject><subject>Biological and medical sciences</subject><subject>CD4-Positive T-Lymphocytes</subject><subject>Cells, Cultured</subject><subject>Culture Media</subject><subject>Deoxyadenosines</subject><subject>Deoxyadenosines - chemistry</subject><subject>Deoxyadenosines - metabolism</subject><subject>Deoxyadenosines - pharmacology</subject><subject>DNA-Directed DNA Polymerase</subject><subject>DNA-Directed DNA Polymerase - drug effects</subject><subject>HIV-1</subject><subject>HIV-1 - drug effects</subject><subject>Human immunodeficiency virus 1</subject><subject>Human viral diseases</subject><subject>Humans</subject><subject>Immunodeficiencies</subject><subject>Immunodeficiencies. 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Antiinfectious agents. Antiparasitic agents</topic><topic>Antiviral Agents</topic><topic>Biological and medical sciences</topic><topic>CD4-Positive T-Lymphocytes</topic><topic>Cells, Cultured</topic><topic>Culture Media</topic><topic>Deoxyadenosines</topic><topic>Deoxyadenosines - chemistry</topic><topic>Deoxyadenosines - metabolism</topic><topic>Deoxyadenosines - pharmacology</topic><topic>DNA-Directed DNA Polymerase</topic><topic>DNA-Directed DNA Polymerase - drug effects</topic><topic>HIV-1</topic><topic>HIV-1 - drug effects</topic><topic>Human immunodeficiency virus 1</topic><topic>Human viral diseases</topic><topic>Humans</topic><topic>Immunodeficiencies</topic><topic>Immunodeficiencies. Immunoglobulinopathies</topic><topic>Immunopathology</topic><topic>Infectious diseases</topic><topic>Medical sciences</topic><topic>Microbial Sensitivity Tests</topic><topic>Pharmacology. 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</abstract><cop>Washington, DC</cop><pub>American Society for Microbiology</pub><pmid>17548498</pmid><doi>10.1128/aac.00277-07</doi><tpages>8</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0066-4804 |
| ispartof | Antimicrobial Agents and Chemotherapy, 2007-08, Vol.51 (8), p.2701-2708 |
| issn | 0066-4804 1098-6596 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_70740075 |
| source | MEDLINE; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; PubMed Central |
| subjects | Anti-HIV Agents Anti-HIV Agents - chemistry Anti-HIV Agents - metabolism Anti-HIV Agents - pharmacology Antibiotics. Antiinfectious agents. Antiparasitic agents Antiviral Agents Biological and medical sciences CD4-Positive T-Lymphocytes Cells, Cultured Culture Media Deoxyadenosines Deoxyadenosines - chemistry Deoxyadenosines - metabolism Deoxyadenosines - pharmacology DNA-Directed DNA Polymerase DNA-Directed DNA Polymerase - drug effects HIV-1 HIV-1 - drug effects Human immunodeficiency virus 1 Human viral diseases Humans Immunodeficiencies Immunodeficiencies. Immunoglobulinopathies Immunopathology Infectious diseases Medical sciences Microbial Sensitivity Tests Pharmacology. Drug treatments Reverse Transcriptase Inhibitors Reverse Transcriptase Inhibitors - chemistry Reverse Transcriptase Inhibitors - metabolism Reverse Transcriptase Inhibitors - pharmacology Tritium - metabolism Viral diseases Viral diseases of the lymphoid tissue and the blood. Aids Zidovudine - metabolism Zidovudine - pharmacology |
| title | Activity against Human Immunodeficiency Virus Type 1, Intracellular Metabolism, and Effects on Human DNA Polymerases of 4′-Ethynyl-2-Fluoro-2′-Deoxyadenosine |
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