Prognostic Significance of Nuclear ING3 Expression in Human Cutaneous Melanoma

Purpose: The novel tumor-suppressor ING3 has been shown to modulate transcription, cell cycle control, and apoptosis. Our previous study showed that ING3 promotes UV-induced apoptosis via the Fas/caspase-8–dependent pathway in melanoma cells. To investigate the putative role of ING3 in the developme...

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Veröffentlicht in:	Clinical cancer research 2007-07, Vol.13 (14), p.4111-4116
Hauptverfasser:	YEMIN WANG, DAI, Derek L, MARTINKA, Magdalena, GANG LI
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Biological and medical sciences Biomarkers, Tumor - analysis Cell Nucleus - genetics Cell Nucleus - pathology Dermatology Female Genes, Tumor Suppressor Homeodomain Proteins - genetics Humans immunohistochemistry ING3 Male Medical sciences melanoma Melanoma - genetics Melanoma - pathology Middle Aged Oligonucleotide Array Sequence Analysis Pharmacology. Drug treatments Prognosis Skin Neoplasms - genetics Skin Neoplasms - pathology tissue microarray Trans-Activators - genetics Tumor Suppressor Proteins Tumors of the skin and soft tissue. Premalignant lesions
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