Development of biodegradable electrospun scaffolds for dermal replacement

Abstract Our objective is to develop a synthetic biodegradable replacement dermal substitute for tissue engineering of skin and oral mucosa. Our in vivo criteria were that candidate scaffolds should allow surrounding cells to migrate fully into the scaffolds, enabling vasculogenesis and remodelling...

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Veröffentlicht in:	Biomaterials 2008-07, Vol.29 (21), p.3091-3104
Hauptverfasser:	Blackwood, Keith A, McKean, Rob, Canton, Irene, Freeman, Christine O, Franklin, Kirsty L, Cole, Daryl, Brook, Ian, Farthing, Paula, Rimmer, Stephen, Haycock, John W, Ryan, Anthony J, MacNeil, Sheila
Format:	Artikel
Sprache:	eng
Schlagworte:	Advanced Basic Science Animals Biocompatibility Biocompatible Materials - chemistry Biocompatible Materials - pharmacology Cell Survival - drug effects Cells, Cultured Dentistry Electrospinning Endothelial Cells - cytology Fibroblasts - cytology Humans Keratinocytes - cytology Lactic Acid - chemistry Male Microscopy, Electron, Scanning Microscopy, Fluorescence Polyesters - chemistry Polyglycolic Acid - chemistry Polymers Rats Rats, Wistar Rhodamines - chemistry Skin, Artificial Tissue engineering Tissue Engineering - methods
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