Hypoxia contributes to development of recurrent endometrial carcinoma

Tumor hypoxia can trigger the induction of angiogenesis. High microvessel density (MVD) as well as hypoxia-inducible factor-1α (HIF-1α) have been related to recurrent disease and tumor aggressiveness, respectively. In this study, MVD and hypoxic status were investigated in primary and recurrent endo...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	International journal of gynecological cancer 2007-07, Vol.17 (4), p.897-904
Hauptverfasser:	Pijnenborg, J. M.A., Wijnakker, M., Hagelstein, J., Delvoux, B., Groothuis, P. G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Aged, 80 and over Antigens, Neoplasm - biosynthesis CA-IX Cancer Carbonic Anhydrase IX Carbonic Anhydrases - biosynthesis Carcinoma, Endometrioid - blood supply Carcinoma, Endometrioid - metabolism Carcinoma, Endometrioid - pathology Cell Hypoxia - physiology Cell Line, Tumor Endometrial cancer endometrial carcinoma Endometrial Neoplasms - blood supply Endometrial Neoplasms - metabolism Endometrial Neoplasms - pathology Female HIF-1a Humans Hypoxia Hypoxia-Inducible Factor 1, alpha Subunit - biosynthesis Hypoxia-Inducible Factor 1, alpha Subunit - metabolism Lymphatic Metastasis Middle Aged MVD Neoplasm Recurrence, Local - blood supply Neoplasm Recurrence, Local - genetics Neoplasm Recurrence, Local - metabolism Neoplasm Recurrence, Local - pathology Neovascularization, Pathologic - metabolism Neovascularization, Pathologic - pathology Proteins recurrence Tumor Suppressor Protein p53 - biosynthesis Tumor Suppressor Protein p53 - metabolism Tumors
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!