Differential gene expression in the peripheral zone compared to the transition zone of the human prostate gland

Gene expression profiles may lend insight into whether prostate adenocarcinoma (CaP) predominantly occurs in the peripheral zone (PZ) compared to the transition zone (TZ). From human prostates, tissue sets consisting of PZ and TZ were isolated to investigate whether there is a differential level of...

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Veröffentlicht in:	Prostate cancer and prostatic diseases 2008-06, Vol.11 (2), p.173-180
Hauptverfasser:	Noel, E E, Ragavan, N, Walsh, M J, James, S Y, Matanhelia, S S, Nicholson, C M, Lu, Y-J, Martin, F L
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenocarcinoma Adenocarcinoma - genetics Adenocarcinoma - metabolism Adenocarcinoma - pathology Aged Biomedical and Life Sciences Biomedicine Cancer Research Cell adhesion DNA microarrays Gene expression Gene Expression Profiling Gene Expression Regulation, Neoplastic Genetic aspects Genomes Humans Male Methods Middle Aged Molecular modelling Neoplasm Proteins - biosynthesis Neoplasm Proteins - genetics Neurogenesis Organ Specificity original-article Physiological aspects Prostate Prostate - metabolism Prostate - pathology Prostate cancer Prostatic Neoplasms - genetics Prostatic Neoplasms - metabolism Prostatic Neoplasms - pathology Reverse Transcriptase Polymerase Chain Reaction RNA, Messenger - biosynthesis RNA, Messenger - genetics RNA, Neoplasm - biosynthesis RNA, Neoplasm - genetics RNA-directed DNA polymerase Signal transduction Signal Transduction - genetics Transcription, Genetic
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