NK resistance of tumor cells from multiple myeloma and chronic lymphocytic leukemia patients: implication of HLA-G

Exploiting the antitumor effect of natural killer (NK) cells has regained interest in light of data from preclinical and clinical work on the potential of alloreactive NK cells. Multiple myeloma (MM) and chronic lymphocytic leukemia (CLL) represent the two most prevalent adult hematological malignan...

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Veröffentlicht in:	Leukemia 2008-05, Vol.22 (5), p.998-1006
Hauptverfasser:	Maki, G, Hayes, G M, Naji, A, Tyler, T, Carosella, E D, Rouas-Freiss, N, Gregory, S A
Format:	Artikel
Sprache:	eng
Schlagworte:	Antibodies Anticancer properties Antigens, Neoplasm Antitumor activity Biological and medical sciences Bone marrow Cancer Research Care and treatment Chronic lymphocytic leukemia Critical Care Medicine Cytokines Cytotoxicity, Immunologic Fetuses Health aspects Hematologic and hematopoietic diseases Hematology Histocompatibility antigen HLA Histocompatibility Antigens Class I - analysis Histocompatibility Antigens Class I - genetics Histocompatibility Antigens Class I - immunology HLA Antigens - analysis HLA Antigens - genetics HLA Antigens - immunology HLA-G Antigens Humans Immunodeficiencies. Immunoglobulinopathies Immunoglobulinopathies Immunologic Surveillance Immunopathology Immunosurveillance Immunotherapy Intensive Internal Medicine Killer Cells, Natural - immunology Leukemia Leukemia, Lymphocytic, Chronic, B-Cell - immunology Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis Lymphatic leukemia Medical sciences Medicine Medicine & Public Health Molecular modelling Multiple myeloma Multiple Myeloma - immunology Natural killer cells Oncology original-article Patients Proteins RNA, Neoplasm - analysis Stem cell transplantation Transcription Tumor cells Tumor Escape Tumors Western Hemisphere
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