Comparison of antioxidant enzymes in saliva of elderly smokers and non-smokers

Comparison of antioxidant enzymes in saliva of elderly smokers and non-smokers

Objectives:  This study was designed to compare the levels of copper/zinc superoxide dismutase (Cu/Zn SOD), peroxidase (POx) and glutathione peroxidase (GSH‐Px) in saliva of smokers and those in saliva of non‐smokers. Methods:  Unstimulated saliva samples were collected from 88 elderly males (65 yea...

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Veröffentlicht in:Gerodontology 2006-03, Vol.23 (1), p.38-42
Hauptverfasser: Kanehira, Takashi, Shibata, Kouichi, Kashiwazaki, Haruhiko, Inoue, Nobuo, Morita, Manabu
Format: Artikel
Sprache:eng
Schlagworte:
Age Factors
Aged
antioxidant enzymes
Antioxidants - analysis
cigarette smoke
Dentistry
elderly
Glutathione Peroxidase - analysis
Humans
Male
Peroxidase - analysis
saliva
Saliva - chemistry
Saliva - enzymology
Smoking - adverse effects
Smoking - metabolism
Superoxide Dismutase - analysis
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Zusammenfassung:Objectives:  This study was designed to compare the levels of copper/zinc superoxide dismutase (Cu/Zn SOD), peroxidase (POx) and glutathione peroxidase (GSH‐Px) in saliva of smokers and those in saliva of non‐smokers. Methods:  Unstimulated saliva samples were collected from 88 elderly males (65 years old or over) who visited a private dental clinic. Forty‐four subjects were current smokers (more than 20 cigarettes daily for at least 30 years) and 44 were non‐smokers. The levels of salivary thiocyanate, Cu/Zn SOD, GSH‐Px, and POx activity were measured using standard procedures. Results:  The mean levels of salivary thiocyanate (SCN−) and SOD were significantly higher (p 
ISSN:0734-0664
1741-2358
DOI:10.1111/j.1741-2358.2006.00077.x