Central neurocytoma responsive to topotecan, ifosfamide, carboplatin
A 5‐year‐old male presented with spinal cord drop metastasis from a recurrent neurocytoma. Topotecan (0.5 mg/m2) and carboplatin (250 mg/m2) were administered on days 1–3 and ifosfamide (1,800 mg/m2) on days 1–5, every 21 days, for three cycles and resulted in complete response without severe compli...
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| Veröffentlicht in: | Pediatric Blood & Cancer 2008-07, Vol.51 (1), p.137-140 |
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| container_title | Pediatric Blood & Cancer |
| container_volume | 51 |
| creator | Amini, Elham Roffidal, Tina Lee, Alice Fuller, Gregory N. Mahajan, Anita Ketonen, Leena Kobrinsky, Nathan Cairo, Mitchell S. Wells, Robert J. Wolff, Johannes E.A. |
| description | A 5‐year‐old male presented with spinal cord drop metastasis from a recurrent neurocytoma. Topotecan (0.5 mg/m2) and carboplatin (250 mg/m2) were administered on days 1–3 and ifosfamide (1,800 mg/m2) on days 1–5, every 21 days, for three cycles and resulted in complete response without severe complications. A literature review yielded 20 patients with central neurocytoma but no complete responses. The complete response of central neurocytoma to chemotherapy only reported here should be helpful to those caring for patients with this rare tumor. Pediatr Blood Cancer 2008;51:137–140. © 2008 Wiley‐Liss, Inc. |
| doi_str_mv | 10.1002/pbc.21551 |
| format | Article |
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| language | eng |
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| subjects | Antineoplastic Combined Chemotherapy Protocols - therapeutic use Carboplatin chemotherapy Child, Preschool Disease-Free Survival Humans Ifosfamide Magnetic Resonance Imaging Male neurocytoma Neurocytoma - diagnosis Neurocytoma - drug therapy pediatric Remission Induction Topotecan |
| title | Central neurocytoma responsive to topotecan, ifosfamide, carboplatin |
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