Enhanced cutaneous hypersensitivity reactions are associated with ovine high and low cortisol responsiveness to acute endotoxin challenge

Inbred rodent studies have demonstrated that cutaneous hypersensitivity reactions are exacerbated in stress-susceptible, and attenuated in stress-resistant strains of mice. This physiological response was, in part, mediated by activation of the hypothalamic-pituitary-adrenal axis during the acute re...

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Veröffentlicht in:	Veterinary dermatology 2008-06, Vol.19 (3), p.174-183
Hauptverfasser:	You, Qiumei, Karrow, Niel A, Quinton, Margaret, Mallard, Bonnie A, Boermans, Herman J
Format:	Artikel
Sprache:	eng
Schlagworte:	abiotic stress Animals benzene Candida albicans cortisol endotoxins Endotoxins - immunology Escherichia coli Female genetic variation glucocorticoids hormone secretion Hydrocortisone - secretion hypersensitivity Hypothalamo-Hypophyseal System - immunology Hypothalamo-Hypophyseal System - physiology Hypothalamo-Hypophyseal System - physiopathology immune response immune system Immunoglobulin G - blood Immunoglobulin G - immunology immunologic factors inflammation Interferon-gamma - blood Interferon-gamma - immunology Interleukin-6 - blood Interleukin-6 - immunology Ovalbumin - immunology pathogenesis phytohemagglutinin Pituitary-Adrenal System - immunology Pituitary-Adrenal System - physiology Pituitary-Adrenal System - physiopathology sheep Sheep - blood sheep breeds sheep diseases Sheep Diseases - immunology Sheep Diseases - microbiology skin diseases
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