Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study
One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature...
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Veröffentlicht in: | Archives of orthopaedic and trauma surgery 2007-08, Vol.127 (6), p.409-416 |
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creator | Mumme, T Gravius, S Andereya, S Marx, R Wirtz, D C Müller-Rath, R |
description | One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature aseptic loosening. Accordingly, an amphiphilic bonding system was developed to prevent hydrolytic debonding in the interface bone-to-bone cement.
Polyethylene cups were cemented in cadaver sheep hips. The hips were prepared with (n = 10) a multilayer bonding system as well as with an improved monolayer bonding system with (n = 10) and without (n = 10) UV-light hardening. The hips were dynamically loaded (10(6) cycles; 3 Hz; upper/lower load 1,500/200 N) and afterwards turned out with a defined strength to determine the interface compound strength. Dynamically loaded cemented cups without using the bonding system (n = 10) function as a control group.
The interface adhesive strength improved significantly by a factor of 1.9 (using the multilayer bonding system) compared to the unconditioned ones (P < or = 0.05); for the monolayer bonding system without (with) UV-light hardening the compound strength was 11.9-fold (> or =22.2-fold) higher (P < or = 0.001).
The bonding system significantly improves the adhesive strength between bone and bone cement in cemented cup arthroplasty. |
doi_str_mv | 10.1007/s00402-007-0340-9 |
format | Article |
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Polyethylene cups were cemented in cadaver sheep hips. The hips were prepared with (n = 10) a multilayer bonding system as well as with an improved monolayer bonding system with (n = 10) and without (n = 10) UV-light hardening. The hips were dynamically loaded (10(6) cycles; 3 Hz; upper/lower load 1,500/200 N) and afterwards turned out with a defined strength to determine the interface compound strength. Dynamically loaded cemented cups without using the bonding system (n = 10) function as a control group.
The interface adhesive strength improved significantly by a factor of 1.9 (using the multilayer bonding system) compared to the unconditioned ones (P < or = 0.05); for the monolayer bonding system without (with) UV-light hardening the compound strength was 11.9-fold (> or =22.2-fold) higher (P < or = 0.001).
The bonding system significantly improves the adhesive strength between bone and bone cement in cemented cup arthroplasty.</description><identifier>ISSN: 0936-8051</identifier><identifier>EISSN: 1434-3916</identifier><identifier>DOI: 10.1007/s00402-007-0340-9</identifier><identifier>PMID: 17492454</identifier><language>eng</language><publisher>Germany: Springer Nature B.V</publisher><subject>Adhesiveness ; Adhesives ; Animals ; Arthroplasty, Replacement, Hip - methods ; Bone Cements ; Cement ; In Vitro Techniques ; Joint surgery ; Polyethylene ; Prosthesis Design</subject><ispartof>Archives of orthopaedic and trauma surgery, 2007-08, Vol.127 (6), p.409-416</ispartof><rights>Springer-Verlag 2007.</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c393t-562853f86693f4d29fde93b5642c0a6c1189d191976018814c56ab1718158b753</citedby><cites>FETCH-LOGICAL-c393t-562853f86693f4d29fde93b5642c0a6c1189d191976018814c56ab1718158b753</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/17492454$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Mumme, T</creatorcontrib><creatorcontrib>Gravius, S</creatorcontrib><creatorcontrib>Andereya, S</creatorcontrib><creatorcontrib>Marx, R</creatorcontrib><creatorcontrib>Wirtz, D C</creatorcontrib><creatorcontrib>Müller-Rath, R</creatorcontrib><title>Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study</title><title>Archives of orthopaedic and trauma surgery</title><addtitle>Arch Orthop Trauma Surg</addtitle><description>One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature aseptic loosening. Accordingly, an amphiphilic bonding system was developed to prevent hydrolytic debonding in the interface bone-to-bone cement.
Polyethylene cups were cemented in cadaver sheep hips. The hips were prepared with (n = 10) a multilayer bonding system as well as with an improved monolayer bonding system with (n = 10) and without (n = 10) UV-light hardening. The hips were dynamically loaded (10(6) cycles; 3 Hz; upper/lower load 1,500/200 N) and afterwards turned out with a defined strength to determine the interface compound strength. Dynamically loaded cemented cups without using the bonding system (n = 10) function as a control group.
The interface adhesive strength improved significantly by a factor of 1.9 (using the multilayer bonding system) compared to the unconditioned ones (P < or = 0.05); for the monolayer bonding system without (with) UV-light hardening the compound strength was 11.9-fold (> or =22.2-fold) higher (P < or = 0.001).
The bonding system significantly improves the adhesive strength between bone and bone cement in cemented cup arthroplasty.</description><subject>Adhesiveness</subject><subject>Adhesives</subject><subject>Animals</subject><subject>Arthroplasty, Replacement, Hip - methods</subject><subject>Bone Cements</subject><subject>Cement</subject><subject>In Vitro Techniques</subject><subject>Joint surgery</subject><subject>Polyethylene</subject><subject>Prosthesis Design</subject><issn>0936-8051</issn><issn>1434-3916</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2007</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><recordid>eNpdkUuLFDEUhYMoTjv6A9xIQHAXvXlW4k4GHwMDbnQdUlW3pmuoStok1TP9762mGgRX98E5h3v5CHnL4SMHaD4VAAWCrS0DqYC5Z2THlVRMOm6ekx04aZgFza_Iq1IeALiwDl6SK94oJ5RWO_J4Ox9yOuKMsdI00LpHOqV4zyrmmYZ-j2U8Ii01Y7yve9pifUSMtE0RabfZQuy3eYyXFfa0Ww405LrP6TCFUk-fKT6x43hMa9bSn16TF0OYCr651Gvy-9vXXzc_2N3P77c3X-5YJ52sTBthtRysMU4Oqhdu6NHJVhslOgim49y6njvuGgPcWq46bULLG265tm2j5TX5sOWuX_5ZsFQ_j6XDaQoR01J8A43Q0phV-P4_4UNaclxv80IYAWClalYV31RdTqVkHPwhj3PIJ8_Bn5n4jYk_t2cm3q2ed5fkpZ2x_-e4QJB_AeZZhqQ</recordid><startdate>20070801</startdate><enddate>20070801</enddate><creator>Mumme, T</creator><creator>Gravius, S</creator><creator>Andereya, S</creator><creator>Marx, R</creator><creator>Wirtz, D C</creator><creator>Müller-Rath, R</creator><general>Springer Nature B.V</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X7</scope><scope>7XB</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20070801</creationdate><title>Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study</title><author>Mumme, T ; Gravius, S ; Andereya, S ; Marx, R ; Wirtz, D C ; Müller-Rath, R</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c393t-562853f86693f4d29fde93b5642c0a6c1189d191976018814c56ab1718158b753</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2007</creationdate><topic>Adhesiveness</topic><topic>Adhesives</topic><topic>Animals</topic><topic>Arthroplasty, Replacement, Hip - methods</topic><topic>Bone Cements</topic><topic>Cement</topic><topic>In Vitro Techniques</topic><topic>Joint surgery</topic><topic>Polyethylene</topic><topic>Prosthesis Design</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Mumme, T</creatorcontrib><creatorcontrib>Gravius, S</creatorcontrib><creatorcontrib>Andereya, S</creatorcontrib><creatorcontrib>Marx, R</creatorcontrib><creatorcontrib>Wirtz, D C</creatorcontrib><creatorcontrib>Müller-Rath, R</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing & Allied Health Database</collection><collection>Health & Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest Central UK/Ireland</collection><collection>ProQuest Central</collection><collection>ProQuest One Community College</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Health & Medical Complete (Alumni)</collection><collection>Nursing & Allied Health Database (Alumni Edition)</collection><collection>Health & Medical Collection (Alumni Edition)</collection><collection>Nursing & Allied Health Premium</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>MEDLINE - Academic</collection><jtitle>Archives of orthopaedic and trauma surgery</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Mumme, T</au><au>Gravius, S</au><au>Andereya, S</au><au>Marx, R</au><au>Wirtz, D C</au><au>Müller-Rath, R</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study</atitle><jtitle>Archives of orthopaedic and trauma surgery</jtitle><addtitle>Arch Orthop Trauma Surg</addtitle><date>2007-08-01</date><risdate>2007</risdate><volume>127</volume><issue>6</issue><spage>409</spage><epage>416</epage><pages>409-416</pages><issn>0936-8051</issn><eissn>1434-3916</eissn><abstract>One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature aseptic loosening. Accordingly, an amphiphilic bonding system was developed to prevent hydrolytic debonding in the interface bone-to-bone cement.
Polyethylene cups were cemented in cadaver sheep hips. The hips were prepared with (n = 10) a multilayer bonding system as well as with an improved monolayer bonding system with (n = 10) and without (n = 10) UV-light hardening. The hips were dynamically loaded (10(6) cycles; 3 Hz; upper/lower load 1,500/200 N) and afterwards turned out with a defined strength to determine the interface compound strength. Dynamically loaded cemented cups without using the bonding system (n = 10) function as a control group.
The interface adhesive strength improved significantly by a factor of 1.9 (using the multilayer bonding system) compared to the unconditioned ones (P < or = 0.05); for the monolayer bonding system without (with) UV-light hardening the compound strength was 11.9-fold (> or =22.2-fold) higher (P < or = 0.001).
The bonding system significantly improves the adhesive strength between bone and bone cement in cemented cup arthroplasty.</abstract><cop>Germany</cop><pub>Springer Nature B.V</pub><pmid>17492454</pmid><doi>10.1007/s00402-007-0340-9</doi><tpages>8</tpages></addata></record> |
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subjects | Adhesiveness Adhesives Animals Arthroplasty, Replacement, Hip - methods Bone Cements Cement In Vitro Techniques Joint surgery Polyethylene Prosthesis Design |
title | Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study |
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