Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study

One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature...

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Veröffentlicht in:Archives of orthopaedic and trauma surgery 2007-08, Vol.127 (6), p.409-416
Hauptverfasser: Mumme, T, Gravius, S, Andereya, S, Marx, R, Wirtz, D C, Müller-Rath, R
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container_end_page 416
container_issue 6
container_start_page 409
container_title Archives of orthopaedic and trauma surgery
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creator Mumme, T
Gravius, S
Andereya, S
Marx, R
Wirtz, D C
Müller-Rath, R
description One of the main causes of cup loosening in cemented total hip replacement is the lack of a hydrolysis stable compound between the hydrophobic bone cement and the hydrophilic acetabular bone stock. Thus, the long-term adhesive strength between bone and bone cement is decreased resulting in premature aseptic loosening. Accordingly, an amphiphilic bonding system was developed to prevent hydrolytic debonding in the interface bone-to-bone cement. Polyethylene cups were cemented in cadaver sheep hips. The hips were prepared with (n = 10) a multilayer bonding system as well as with an improved monolayer bonding system with (n = 10) and without (n = 10) UV-light hardening. The hips were dynamically loaded (10(6) cycles; 3 Hz; upper/lower load 1,500/200 N) and afterwards turned out with a defined strength to determine the interface compound strength. Dynamically loaded cemented cups without using the bonding system (n = 10) function as a control group. The interface adhesive strength improved significantly by a factor of 1.9 (using the multilayer bonding system) compared to the unconditioned ones (P < or = 0.05); for the monolayer bonding system without (with) UV-light hardening the compound strength was 11.9-fold (> or =22.2-fold) higher (P < or = 0.001). The bonding system significantly improves the adhesive strength between bone and bone cement in cemented cup arthroplasty.
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subjects Adhesiveness
Adhesives
Animals
Arthroplasty, Replacement, Hip - methods
Bone Cements
Cement
In Vitro Techniques
Joint surgery
Polyethylene
Prosthesis Design
title Improvement of the long-term adhesive strength between bone cement and bone in cemented cup arthroplasty: ex-vivo study
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