High-Throughput Small Angle X-ray Scattering from Proteins in Solution Using a Microfluidic Front-End

This manuscript presents, for the first time, the method of automated structural analysis of biomolecules in solution on a microfluidic chip. A polymer-based micrototal analysis system for high-throughput Small-Angle X-ray Scattering (SAXS) data collection from biological macromolecules has been dev...

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Veröffentlicht in:	Analytical chemistry (Washington) 2008-05, Vol.80 (10), p.3648-3654
Hauptverfasser:	Toft, K. Nørgaard, Vestergaard, Bente, Nielsen, Søren S, Snakenborg, Detlef, Jeppesen, Mads G, Jacobsen, Jes K, Arleth, Lise, Kutter, Jörg P
Format:	Artikel
Sprache:	eng
Schlagworte:	Analytical chemistry Chemistry Exact sciences and technology Mammals Microfluidics - instrumentation Molecular structure Molecules Proteins Proteins - chemistry Scattering Scattering, Radiation Sodium Dodecyl Sulfate Solutions Spectrometric and optical methods
Online-Zugang:	Volltext
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