Characterization of the chromosomal class A β-lactamase CKO from Citrobacter koseri

Abstract The gene blaCKO encoding the chromosomal class A β-lactamase of Citrobacter koseri was cloned and sequenced. CKO was found to display only 41% identity with SED-1 from Citrobacter sedlakii and 36% with CdiA from Citrobacter amalonaticus (formerly Citrobacter diversus). No transcriptional re...

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Veröffentlicht in:	FEMS microbiology letters 2006-01, Vol.254 (2), p.285-292
Hauptverfasser:	Petrella, Stephanie, Renard, Murielle, Ziental-Gelus, Nathalie, Clermont, Dominique, Jarlier, Vincent, Sougakoff, Wladimir
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Anti-Bacterial Agents - pharmacology beta-Lactamases - genetics beta-Lactamases - metabolism beta-Lactams - pharmacology Chromosomes, Bacterial Citrobacter Citrobacter amalonaticus Citrobacter koseri Citrobacter koseri - classification Citrobacter koseri - drug effects Citrobacter koseri - enzymology Citrobacter koseri - genetics Clinical isolates Humans lactamase Microbial Sensitivity Tests Microbiology Missense mutation Molecular Sequence Data Mutation Polymerase chain reaction Sequence Analysis, DNA Species Specificity Transcription
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