Intratumoral expression of respiratory syncytial virus fusion protein in combination with cytokines encoded by adenoviral vectors as in situ tumor vaccine for colorectal cancer

Although cancers can naturally elicit immune responses, immune ignorance is a common observation preventing immune-mediated elimination of tumor cells. We assessed whether intratumoral expression of respiratory syncytial virus fusion (RSV-F) protein, encoded by a replication-defective adenovirus vec...

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Veröffentlicht in:Molecular cancer therapeutics 2007-07, Vol.6 (7), p.1942-1950
Hauptverfasser: Hoffmann, Dennis, Bayer, Wibke, Grunwald, Thomas, Wildner, Oliver
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Sprache:eng
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