Seizure-like afterdischarges simulated in a model neuron

To explore non-synaptic mechanisms in paroxysmal discharges, we used a computer model of a simplified hippocampal pyramidal cell, surrounded by interstitial space and a "glial-endothelial" buffer system. Ion channels for Na+, K+, Ca2+ and Cl- ion antiport 3Na/Ca, and "active" ion...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Journal of computational neuroscience 2007-04, Vol.22 (2), p.105-128
Hauptverfasser:	Kager, H, Wadman, W J, Somjen, G G
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Calcium - metabolism Computer Simulation Dendrites - drug effects Dendrites - physiology Electric Stimulation - methods Hippocampus - pathology Ion Channels - drug effects Ion Channels - physiology Membrane Potentials - drug effects Membrane Potentials - physiology Membrane Potentials - radiation effects Models, Neurological Potassium - metabolism Potassium - pharmacology Pyramidal Cells - cytology Pyramidal Cells - drug effects Pyramidal Cells - physiopathology Receptors, N-Methyl-D-Aspartate - physiology Seizures - pathology Seizures - physiopathology Sodium - metabolism Sodium - pharmacology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Schreiben Sie den ersten Kommentar!