Amylin deposition in the kidney of patients with diabetic nephropathy

Amylin (islet amyloid peptide) plays a critical role in islet amyloidosis and in the development of β-cell dysfunction in patients with diabetes; however, the involvement of amylin in renal amyloidosis has not been studied. For this reason, we surveyed 149 patients with biopsy-proven diabetic nephro...

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Veröffentlicht in:	Kidney international 2007-07, Vol.72 (2), p.213-218
Hauptverfasser:	Gong, W., Liu, Z.H., Zeng, C.H., Peng, A., Chen, H.P., Zhou, H., Li, L.S.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adult amylin Amyloid - analysis Amyloid - metabolism Amyloidosis - etiology Amyloidosis - pathology Associated diseases and complications Biological and medical sciences Case-Control Studies Cell Proliferation Diabetes. Impaired glucose tolerance Diabetic Nephropathies - pathology diabetic nephropathy Endocrine pancreas. Apud cells (diseases) Endocrinopathies Extracellular Matrix - pathology Female Humans Islet Amyloid Polypeptide Kidney - chemistry Kidney - metabolism Kidneys Male Medical sciences Mesangial Cells - pathology Middle Aged Nephrology. Urinary tract diseases Nephrosclerosis renal pathology Urinary system involvement in other diseases. Miscellaneous
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