Homocysteine, methylenetetrahydrofolate reductase and risk of schizophrenia: a meta-analysis

Elevated plasma homocysteine concentration has been suggested as a risk factor for schizophrenia, but the results of epidemiological studies have been inconsistent. The most extensively studied genetic variant in the homocysteine metabolism is the 677C>T polymorphism in the methylenetetrahydrofol...

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Veröffentlicht in:	Molecular psychiatry 2006-02, Vol.11 (2), p.143-149
Hauptverfasser:	Muntjewerff, J W, Kahn, R S, Blom, H J, den Heijer, M
Format:	Artikel
Sprache:	eng
Schlagworte:	Amino Acid Substitution Behavioral Sciences Biological Psychology Case-Control Studies Enzymatic activity Epidemiology Gene polymorphism Genetic diversity Genetic Predisposition to Disease Genotype & phenotype Homocysteine Homocysteine - blood Humans Medicine Medicine & Public Health Mental disorders Meta-analysis Metabolism Methylenetetrahydrofolate reductase Methylenetetrahydrofolate Reductase (NADPH2) - genetics Methylenetetrahydrofolate Reductase (NADPH2) - metabolism Neurosciences original-article Pharmacotherapy Polymorphism Psychiatry Reference Values Risk Factors Schizophrenia Schizophrenia - blood Schizophrenia - enzymology Schizophrenia - genetics Systematic review
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