A fate map of Tbx1 expressing cells reveals heterogeneity in the second cardiac field

Tbx1 is required for the expansion of second heart field (SHF) cardiac progenitors destined to the outflow tract of the heart. Loss of Tbx1 causes heart defects in humans and mice. We report a novel Tbx1Cre knock‐in allele that we use to fate map Tbx1‐expressing cells during development in conjuncti...

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Veröffentlicht in:	Genesis (New York, N.Y. : 2000) N.Y. : 2000), 2007-07, Vol.45 (7), p.470-475
Hauptverfasser:	Huynh, Tuong, Chen, Li, Terrell, Phillip, Baldini, Antonio
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals cardiovascular development Cell Lineage - physiology Cre-based cell fate mapping Heart - embryology Mice Mice, Inbred C57BL Myocardium - metabolism outflow tract of the heart second heart field T-Box Domain Proteins - biosynthesis T-Box Domain Proteins - genetics Tbx1
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