Using behavioral measurement to assess tumor progression and functional outcome after antiangiogenic treatment in mouse glioma models

The objective of the current study was to investigate the behavioral changes of glioma-bearing nude mice and functional outcome from treatment with a novel antiangiogenesis regimen, which is a combination of monoclonal antibodies against both vascular endothelial growth factor receptor (VEGFR)-1 (MF...

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Veröffentlicht in:	Behavioural brain research 2007-08, Vol.182 (1), p.42-50
Hauptverfasser:	Yang, Hongyan, Chopp, Michael, Zhang, Xuepeng, Jiang, Feng, Zhang, Zhenggang, Kalkanis, Steve, Schallert, Timothy
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antiangiogenesis Antibodies, Monoclonal - therapeutic use Behavior Behavior, Animal - physiology Behavioral psychophysiology Biological and medical sciences Disease Models, Animal Disease Progression Functional outcome Fundamental and applied biological sciences. Psychology Glioma Glioma - drug therapy Glioma - pathology Glioma - physiopathology Humans Medical sciences Mice Mice, Nude Neoplasm Transplantation - methods Neurology Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Quality of life Time Factors Tumors of the nervous system. Phacomatoses Vascular Endothelial Growth Factor A - metabolism Vascular Endothelial Growth Factor Receptor-1 - immunology Vascular Endothelial Growth Factor Receptor-2 - immunology Xenograft Model Antitumor Assays - methods
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