Plasma carnitine ester profiles in Crohn's disease patients characterized for SLC22A4 C1672T and SLC22A5 G-207C genotypes

Crohn's disease (CD) is a chronic inflammatory bowel disorder caused by environmental and genetic factors. The purpose of this study was to analyse the possible influence of functional variants of genes of OCTN cation transporters on the carnitine ester profile of patients with CD. Genotyping f...

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Veröffentlicht in:	British journal of nutrition 2007-08, Vol.98 (2), p.345-350
Hauptverfasser:	Bene, Judit, Komlósi, Katalin, Magyari, Lili, Talián, Gábor, Horváth, Krisztina, Gasztonyi, Beáta, Miheller, Pál, Figler, Mária, Mózsik, Gyula, Tulassay, Zsolt, Melegh, Béla
Format:	Artikel
Sprache:	eng
Schlagworte:	Adolescent Adult Aged Aged, 80 and over Biological and medical sciences biomarkers blood chemistry carnitine Carnitine - analogs & derivatives Carnitine - blood Carnitine - genetics Carnitine ester profile Crohn disease Crohn Disease - blood Crohn Disease - genetics Crohn's disease Deoxyribonucleic acid Disease control disease resistance DNA epidemiology Esters Esters - blood etiology Feeding. Feeding behavior Female Fundamental and applied biological sciences. Psychology gene expression Gene Frequency - genetics Genes Genetic factors genetic polymorphism Genetic Predisposition to Disease - genetics genetic variance Genotype Genotype & phenotype Genotypes Histology homeostasis human genetics Humans lipid metabolism Male Mass spectrometry Metabolic disorders Middle Aged molecular sequence data Mutation Nod2 Signaling Adaptor Protein - genetics NOD2/CARD15 nucleotide sequences OCTN1 OCTN2 Organic Cation Transport Proteins - genetics patients Plasma point mutation Proteins quantitative traits transporters Vertebrates: anatomy and physiology, studies on body, several organs or systems
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