Role of mast cell degranulation in the neural correlates of the immediate allergic reaction in a murine model of asthma

Abstract Experimental airway allergy in mice leads to increased activity in specific hypothalamic and amygdaloid nuclei, and behavioral changes. The experiments described here were designed to determine the role of anaphylactic antibodies, mast cell degranulation, and lung inflammation in the neural...

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Veröffentlicht in:	Brain, behavior, and immunity behavior, and immunity, 2007-08, Vol.21 (6), p.783-790
Hauptverfasser:	Costa-Pinto, Frederico Azevedo, Basso, Alexandre Salgado, Russo, Momtchilo
Format:	Artikel
Sprache:	eng
Schlagworte:	Airways Allergy Allergy and Immunology Amygdala - immunology Amygdala - physiology Analysis of Variance Anaphylaxis - immunology Animals Asthma Asthma - immunology Avoidance Avoidance Learning - physiology Behavior Behavior, Animal - physiology Brain Cell Degranulation - immunology Disease Models, Animal Hypersensitivity - immunology IgE Immune Tolerance - immunology Immunoglobulin E - immunology Lung Male Mast cell Mast Cells - physiology Mice Mice, Inbred BALB C Mice, Inbred C3H Mouse Neuroimmunology Neuroimmunomodulation - immunology Neuroimmunomodulation - physiology Ovalbumin - immunology Paraventricular Hypothalamic Nucleus - immunology Paraventricular Hypothalamic Nucleus - physiology Psychiatry Species Specificity Statistics, Nonparametric
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