Transposon characterization of vancomycin-resistant Enterococcus faecium (VREF) and dissemination of resistance associated with transferable plasmids

Objectives VanA glycopeptide resistance has persisted on broiler farms in the UK despite the absence of the antimicrobial selective pressure, avoparcin. This study aimed to investigate the contribution of horizontal gene transfer of Tn1546 versus clonal spread in the dissemination of the resistance....

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Veröffentlicht in:	Journal of antimicrobial chemotherapy 2007-08, Vol.60 (2), p.263-268
Hauptverfasser:	Garcia-Migura, Lourdes, Liebana, Ernesto, Jensen, Lars Bogø
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Antibiotics. Antiinfectious agents. Antiparasitic agents Biological and medical sciences Blotting, Southern broiler Chemotherapy Chickens - microbiology DNA Primers DNA Transposable Elements - genetics Drug resistance Enterococcus faecium Enterococcus faecium - drug effects Enterococcus faecium - genetics Gene Transfer, Horizontal Genetics Gram-Positive Bacterial Infections - microbiology Gram-Positive Bacterial Infections - veterinary horizontal transfer Lincosamides Livestock Macrolides - pharmacology Medical sciences Peptides Pharmacology. Drug treatments Plasmids - genetics Poultry Diseases - epidemiology Poultry Diseases - microbiology Replicon - genetics replicon typing Reverse Transcriptase Polymerase Chain Reaction Streptogramin B - pharmacology Tn1546 United Kingdom - epidemiology Vancomycin Resistance - genetics Virginiamycin - analogs & derivatives Virginiamycin - pharmacology
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