Vitronectin: Growth Factor Complexes Hold Potential as a Wound Therapy Approach

Topical administration of growth factors has displayed some potential in wound healing, but variable efficacy, high doses, and costs have hampered their implementation. Moreover, this approach ignores the fact that wound repair is driven by interactions between multiple growth factors and extracellu...

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Veröffentlicht in:	Journal of investigative dermatology 2008-06, Vol.128 (6), p.1535-1544
Hauptverfasser:	Upton, Zee, Cuttle, Leila, Noble, Anthony, Kempf, Margit, Topping, Gemma, Malda, Jos, Xie, Yan, Mill, Julie, Harkin, Damien G., Kravchuk, Olena, Leavesley, David I., Kimble, Roy M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Cell Movement Extracellular Matrix - metabolism Gene Expression Regulation Humans Insulin-Like Growth Factor Binding Protein 3 - metabolism Insulin-Like Growth Factor Binding Protein 5 - metabolism Integrin alphaV - metabolism Intercellular Signaling Peptides and Proteins - metabolism Keratinocytes - cytology Keratinocytes - metabolism Skin - embryology Skin - metabolism Swine Vitronectin - metabolism Vitronectin - physiology Wound Healing
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