Role of Serum Fetuin-A, a Major Inhibitor of Systemic Calcification, in Pseudoxanthoma Elasticum

Pseudoxanthoma elasticum (PXE) is a hereditary disorder of the connective tissue affecting the skin, retina, and cardiovascular system and characterized by progressive calcification of abnormal and fragmented elastic fibers in the extracellular matrix. The aim of the present study was to investigate...

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Veröffentlicht in:	Clinical chemistry (Baltimore, Md.) Md.), 2006-02, Vol.52 (2), p.227-234
Hauptverfasser:	Hendig, Doris, Schulz, Veronika, Arndt, Marius, Szliska, Christiane, Kleesiek, Knut, Gotting, Christian
Format:	Artikel
Sprache:	eng
Schlagworte:	alpha-2-HS-Glycoprotein Analytical, structural and metabolic biochemistry Biological and medical sciences Blood Blood & organ donations Blood Proteins - analysis Blood Proteins - genetics Blood Proteins - physiology Calcification Calcinosis - etiology Calcinosis - genetics Cardiovascular system Connective tissue DNA - analysis DNA Mutational Analysis Enzyme-Linked Immunosorbent Assay Extracellular matrix Female Fibers Fundamental and applied biological sciences. Psychology Genes Germany Glycoproteins Humans Investigative techniques, diagnostic techniques (general aspects) Male Males Medical sciences Metabolism Middle Aged Mineralization Multidrug Resistance-Associated Proteins - genetics Mutation Patients Pedigree Polymorphism, Restriction Fragment Length Proteins Pseudoxanthoma Elasticum - blood Pseudoxanthoma Elasticum - complications Pseudoxanthoma Elasticum - genetics Signal transduction
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