Pathological and molecular predictors of the response of rectal cancer to neoadjuvant radiochemotherapy

The prediction of sensitivity and resistance to neoadjuvant therapy has great potential value for many tumour sites. A neoadjuvant regimen is increasingly the gold standard in rectal cancer management and the aim of this review was to highlight predictive markers currently assessed and evaluate thei...

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Veröffentlicht in:	European journal of surgical oncology 2006-02, Vol.32 (1), p.55-64
Hauptverfasser:	Smith, F.M., Reynolds, J.V., Miller, N., Stephens, R.B., Kennedy, M.J.
Format:	Artikel
Sprache:	eng
Schlagworte:	Biomarkers, Tumor - genetics Biomarkers, Tumor - metabolism Chemotherapy DNA, Neoplasm - genetics Gene Expression Genes, bcl-2 - physiology Genes, p53 - physiology Humans Neoadjuvant Therapy Neoplasm Staging Predict Radiotherapy Radiotherapy, Adjuvant Rectal cancer Rectal Neoplasms - drug therapy Rectal Neoplasms - metabolism Rectal Neoplasms - pathology Rectal Neoplasms - radiotherapy Response Treatment Outcome
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