Role of Matrix Metalloproteinases in HaCaT Keratinocytes Apoptosis Induced by Loxosceles Venom Sphingomyelinase D

Envenomation by the spider Loxosceles (brown spider) can result in dermonecrosis and severe ulceration. We have previously shown that Loxosceles sphingomyelinase D (SMaseD), the enzyme responsible for these pathological effects, induced expression of matrix metalloproteinase-9 (MMP-9), which is poss...

Ausführliche Beschreibung

Bibliographische Detailangaben

Veröffentlicht in:	Journal of investigative dermatology 2006-01, Vol.126 (1), p.61-68
Hauptverfasser:	Paixão-Cavalcante, Danielle, van den Berg, Carmen W., de Freitas Fernandes-Pedrosa, Matheus, Gonçalves de Andrade, Rute M., Tambourgi, Denise V.
Format:	Artikel
Sprache:	eng
Schlagworte:	Annexin A5 - metabolism Apoptosis Biomarkers - analysis Cell Line, Transformed Humans Keratinocytes - drug effects Keratinocytes - enzymology Matrix Metalloproteinase 2 - metabolism Matrix Metalloproteinase 9 - metabolism Phosphoric Diester Hydrolases - pharmacology Propidium - metabolism Spider Venoms - enzymology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!