Trophic effects of keratinocytes on the axonal development of sensory neurons in a coculture model

The epidermis, the outermost structure of the skin, fulfils important roles as a physical barrier between the organism and its environment and as a neuroendocrine, immune and sensory organ. It is innervated by unmyelinated sensory fibres conveying nociceptive and thermoceptive information. Little is...

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Veröffentlicht in:	The European journal of neuroscience 2007-07, Vol.26 (1), p.113-125
Hauptverfasser:	Ulmann, Lauriane, Rodeau, Jean-Luc, Danoux, Louis, Contet-Audonneau, Jean-Luc, Pauly, Gilles, Schlichter, Rémy
Format:	Artikel
Sprache:	eng
Schlagworte:	Adenosine Triphosphate - pharmacology Animals axonal growth Axons - physiology Axons - ultrastructure Brain-Derived Neurotrophic Factor - pharmacology calcium Calcium - physiology Capsaicin - pharmacology Cell Line coculture Coculture Techniques Culture Media Ganglia, Spinal - cytology Image Processing, Computer-Assisted Immunohistochemistry keratinocytes Keratinocytes - physiology Keratinocytes - ultrastructure Nerve Growth Factors - pharmacology Neurons, Afferent - physiology Neurons, Afferent - ultrastructure rat Rats Rats, Wistar sensory neurons Substance P - metabolism
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