Expression of two temporally distinct microglia-related gene clusters after spinal cord injury

The dual role of microglia in cytotoxicity and neuroprotection is believed to depend on the specific, temporal expression of microglial‐related genes. To better clarify this issue, we used high‐density oligonucleotide microarrays to examine microglial gene expression after spinal cord injury (SCI) i...

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Veröffentlicht in:	Glia 2006-03, Vol.53 (4), p.420-433
Hauptverfasser:	Byrnes, Kimberly R., Garay, Jorge, Di Giovanni, Simone, De Biase, Andrea, Knoblach, Susan M., Hoffman, Eric P., Movsesyan, Vilen, Faden, Alan I.
Format:	Artikel
Sprache:	eng
Schlagworte:	Acetophenones - pharmacology Animals Biological and medical sciences Biomarkers Blotting, Western C1qB Cells, Cultured chemokine contusion cytokine Data Interpretation, Statistical Fundamental and applied biological sciences. Psychology Galectin 3 - genetics Galectin-3 Gene Expression - physiology Gene Expression Profiling Hyaluronan Receptors - genetics Immunohistochemistry inflammation Inflammation Mediators - physiology Isolated neuron and nerve. Neuroglia Male Membrane Transport Proteins - genetics microarray Microglia - physiology Mitochondrial Proteins Multigene Family - genetics NADPH Oxidases - genetics Oligonucleotide Array Sequence Analysis p22phox Phosphoproteins - genetics Rats Rats, Sprague-Dawley Reverse Transcriptase Polymerase Chain Reaction Spinal Cord Injuries - genetics Spinal Cord Injuries - pathology Vertebrates: nervous system and sense organs
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