Invasion is a genetic program regulated by transcription factors

The invasive and metastatic behaviour of tumours impacts crucially on the clinical management of cancer. Accordingly, it is important to understand the regulation of tumour cell invasiveness. Genetic analysis of worms, Drosophila and mice has provided evidence that invasion is a genetic pathway regu...

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Veröffentlicht in:	Current opinion in genetics & development 2006-02, Vol.16 (1), p.65-70
Hauptverfasser:	Ozanne, Bradford W, Spence, Heather J, McGarry, Lynn C, Hennigan, Robert F
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Drosophila Gene Expression Profiling Gene Expression Regulation, Neoplastic Genes, fos Humans Neoplasm Invasiveness - genetics Oncogenes Transcription Factor AP-1 - genetics Transcription Factors - genetics
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