Arterial stiffening and cardiac hypertrophy in a new rat model of type 2 diabetes

Background We determined the effects of NIDDM on haemodynamic parameters describing arterial wall elasticity and cardiac hypertrophy in rats administered streptozotocin (STZ) and nicotinamide (NA), using the aortic impedance analysis. Methods Male Wistar rats at 2 months were administered intraper...

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Veröffentlicht in:	European journal of clinical investigation 2006-01, Vol.36 (1), p.1-7
Hauptverfasser:	Chang, K.-C., Tseng, C.-D., Chou, T.-F., Cho, Y.-L., Chi, T.-C., Su, M.-J., Tseng, Y.-Z.
Format:	Artikel
Sprache:	eng
Schlagworte:	Animals Aorta - physiopathology Aortic distensibility aortic input impedance Biological and medical sciences Cardiomegaly - physiopathology diabetes mellitus type 2 Diabetes Mellitus, Experimental - physiopathology Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Diabetic Angiopathies - physiopathology Elasticity Electrophoresis, Polyacrylamide Gel Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance General aspects Hemodynamics Male Medical sciences Pulsatile Flow pulse wave reflection Rats Rats, Wistar streptozotocin-nicotinamide diabetic rats Vascular Resistance
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