Citric acid prolongs the gastro-retention of a floating dosage form and increases bioavailability of riboflavin in the fasted state

A floating dosage form based on calcium alginate beads has been developed. Riboflavin, was selected as the model drug and successfully incorporated into calcium alginate beads. The aims of the current study were to: (a) assess the influence of prolonged gastro-retention on the bioavailability of rib...

Ausführliche Beschreibung