Truths and myths of oocyte sensitivity to controlled rate freezing

Abstract The mammalian oocyte is especially sensitive to cryopreservation. Because of its size and physiology, it can easily undergo cell death or sub-lethal damage as a consequence of intracellular ice formation, increase in the concentration of solutes and other undesired effects during the conver...

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Veröffentlicht in:	Reproductive biomedicine online 2007, Vol.15 (1), p.24-30
Hauptverfasser:	Coticchio, G, Bonu, MA, Sciajno, R, Sereni, E, Bianchi, V, Borini, A
Format:	Artikel
Sprache:	eng
Schlagworte:	calcium cryopreservation Cryopreservation - methods cryoprotectant Cryoprotective Agents Female Freezing Humans intracellular ice formation Obstetrics and Gynecology oocyte Oocytes - cytology Oocytes - physiology solute concentration
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