Elevated Peroxiredoxin 1, but not NF-E2–Related Factor 2, Is an Independent Prognostic Factor for Disease Recurrence and Reduced Survival in Stage I Non–Small Cell Lung Cancer

Purpose: Lung cancer is the leading cause of cancer death with chance of survival restricted to a subset of non–small cell lung cancer (NSCLC) patients able to undergo surgical resection. However, the recurrence rate of NSCLC after surgery remains high with few prognostic indicators of clinical outc...

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Veröffentlicht in:	Clinical cancer research 2007-07, Vol.13 (13), p.3875-3882
Hauptverfasser:	KIM, Joo-Heon, BOGNER, Paul N, RAMNATH, Nithya, PARK, Yoorim, YU, Jihnhee, PARK, Young-Mee
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Antineoplastic agents Biological and medical sciences Carcinoma, Non-Small-Cell Lung - genetics Carcinoma, Non-Small-Cell Lung - mortality Carcinoma, Non-Small-Cell Lung - pathology Disease-Free Survival Female Gene Expression Regulation, Neoplastic Humans Lung Neoplasms - metabolism Lung Neoplasms - mortality Lung Neoplasms - pathology Male Medical sciences Middle Aged NF-E2-Related Factor 2 - biosynthesis Non–small cell lung cancer Nrf2 Peroxidases - biosynthesis Peroxiredoxins Pharmacology. Drug treatments Pneumology Prognosis Prx1 Recurrence Regression Analysis Stage I Surgery Survival Treatment Outcome Tumors of the respiratory system and mediastinum
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