Semisolid Systems Containing Propolis for the Treatment of Periodontal Disease: In Vitro Release Kinetics, Syringeability, Rheological, Textural, and Mucoadhesive Properties

Formulations containing poloxamer 407 (P407), carbopol 934P (C934P), and propolis extract (PE) were designed for the treatment of periodontal disease. Gelation temperature, in vitro drug release, rheology, hardness, compressibility, adhesiveness, mucoadhesion, and syringeability of formulations were...

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Veröffentlicht in:	Journal of pharmaceutical sciences 2007-08, Vol.96 (8), p.2074-2089
Hauptverfasser:	Bruschi, Marcos L., Jones, David S., Panzeri, Heitor, Gremião, Maria P.D., de Freitas, Osvaldo, Lara, Elza H.G.
Format:	Artikel
Sprache:	eng
Schlagworte:	Adhesives - chemistry Adhesives - therapeutic use Anti-Infective Agents - chemistry Anti-Infective Agents - therapeutic use biodegradable polymers Biological and medical sciences buccal Drug Delivery Systems Gels General pharmacology hydrogels In Vitro Techniques injectables Kinetics mechanical properties Medical sciences natural products oral drug delivery Periodontal Diseases - drug therapy Pharmaceutical technology. Pharmaceutical industry Pharmacology. Drug treatments Propolis - chemistry Propolis - therapeutic use Rheology Temperature Viscosity
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